中华检验医学杂志2024,Vol.47Issue(11) :1237-1241.DOI:10.3760/cma.j.cn114452-20240130-00059

肿瘤易感基因检测策略的思考

Strategies for cancer susceptibility gene testing

姜惠琴 郭玮
中华检验医学杂志2024,Vol.47Issue(11) :1237-1241.DOI:10.3760/cma.j.cn114452-20240130-00059

肿瘤易感基因检测策略的思考

Strategies for cancer susceptibility gene testing

姜惠琴 1郭玮1
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作者信息

  • 1. 复旦大学附属中山医院检验科,上海 200032
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摘要

为探讨肿瘤易感基因检测的普及所引发的策略层面的争议和思考,该文围绕肿瘤易感基因检测的受检人群、检测基因和组合以及检测方法等,结合最新研究进展、临床实践经验及专家观点,阐述不同策略选择时的考量因素,同时探讨当前肿瘤易感基因检测面临的挑战.肿瘤易感基因检测在肿瘤预防及个体化诊疗方面具有重要意义,然而在临床实践中必须全面考虑各种因素,以推动其良性发展及广泛应用.

Abstract

To explore the controversies and considerations at the strategic level triggered by the popularization of cancer susceptibility gene testing,this article focuses on the testing population,gene panel,and testing methods.By integrating the latest research advances,clinical practice experiences,and expert opinions,it describes the factors to consider when selecting different strategies.Concurrently,the article discusses the current challenges in cancer susceptibility gene testing.While cancer susceptibility gene testing holds significant importance in cancer prevention and individualized treatment,comprehensive consideration of various factors in clinical practice is essential for promoting its beneficial development and broader application.

关键词

肿瘤综合征,遗传性/基因检测/易感基因

Key words

Neoplastic syndromes,hereditary/Gene test/Susceptible gene

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出版年

2024
中华检验医学杂志
中华医学会

中华检验医学杂志

CSTPCD北大核心
影响因子:1.402
ISSN:1009-9158
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