Application of mass cytometry for clinical diagnosis,treatment and research in pediatric diseases
Mass cytometry by time of flight(CyTOF)combines traditional flow cytometry with mass spectrometry,allowing for high-throughput,multiplexed measurements of up to 40 parameters.It offers advantages such as unique metal label tags,no need for compensation calculations,high throughput,and diversified data processing.CyTOF has been applied in many fields of medicine,including signaling pathways,growth and development,tumor microenvironments,autoimmune diseases,infections,immunotherapy,and organ transplantation.This article reviews recent progress in the application of CyTOF in the clinical diagnosis,treatment,and research of pediatric diseases to enhance its utility in diagnosis and treatment.
Flow cytometryMass spectrometryMass cytometry by time of flightPediatricsImmune systemTumor
万方数据
维普
