Vaginal microecological characteristics of ovarian cancer patients complicated with infectious vaginitis and risk factors
OBJECTIVE To explore the vaginal microecological characteristics of the ovarian cancer(OC)patients complicated with infectious vaginitis(IV)and analyze the risk factors.METHODS Totally 238 OC patients who were treated in Ganzhou People's Hospital from Jun 2020 to Feb 2023 were recruited as the research subjects and were divided into the infection group with 72 cases and the non-infection group with 166 cases according to the sta-tus of complication with IV.The incidence of IV and vaginal microecological characteristics of the OC patients were statistically analyzed.Univariate analysis and multivariate logistic analysis were performed for the risk fac-tors for the IV in the OC patients.RESULTS The incidence of IV was 30.25％(72/238)among the OC patients.Among the 72 OC patients complicated with IV,there were 32(44.44％)cases of vaginal candidiasis,26(36.11％)cases of bacterial vaginitis,8(11.11％)cases of mixed infection,5(6.94％)cases of trichomoniasis vaginitis and 1(1.39％)case of aerobic bacteria vaginitis.Multivariate logistic regression analysis showed that the no less than 50 years of age,history of vaginitis,chemotherapy,frequency of sexual intercourse no less than twice per week,education level lower than junior high school,serum C-reactive protein(CRP)no less than 10 mg/L and albumin(ALB)level less than 30 g/L were the risk factors for IV in the OC patients(P＜0.05).CONCLUSION The incidence of IV is high among the OC patients.Ther patients who are infected with vaginal Candida are dominant,followed by the patients with bacterial vaginitis.The occurrence of IV is associated with the age,history of vaginitis,chemotherapy,frequency of sexual intercourse,education level,serum CRP and ALB.
NETL
NSTL
万方数据
维普
