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人偏肺病毒感染研究进展

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人偏肺病毒属于副粘病毒科,肺病毒亚科,偏肺病毒属,为有包膜的单链负RNA病毒.能够引起各年龄段人群感染,多表现为轻度自限性疾病.在免疫功能低下人群中可进展为重症肺炎、多器官功能衰竭,甚至导致死亡.主要通过呼吸道和接触传播,主要依靠核酸检测确诊,无特异性的抗病毒药物,主要以支持治疗为主.尚无疫苗上市.
Progress of research on human metapneumovirus infection
Human metapneumovirus,a single stranded negative RNA virus with an envelope,belongs to the family Pa-ramyxoviridae,subfamily Pneumoviruses,and genus Polypneumovirus.It often causes infections among the population of all age groups,most of the population manifest as mild self-limiting diseases,which may progress to severe pneumonia,multiple organ failure and even lead to death among the immunocompromised population.The respiratory tract and con-tact were the major transmission routes,nucleic acid test was the major diagnostic mean.There are no specific antiviral drugs,and supportive treatment is dominant.There has not been vaccine available yet.

Human metapneumovirusInfectionEtiologyEpidemiologyPathogenesisClinical manifestationDiagnosis and treatment

傅家祺、蒋荣猛

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北京大学医学部,北京 100015

首都医科大学附属北京地坛医院感染中心,北京 100015

人偏肺病毒 感染 病原学 流行病学 发病机制 临床表现 诊断和治疗

2022年北京市高层次公共卫生技术人才建设项目

学科带头人-01-02

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(2)
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