人偏肺病毒感染研究进展
Progress of research on human metapneumovirus infection
傅家祺 1蒋荣猛2
作者信息
- 1. 北京大学医学部,北京 100015
- 2. 首都医科大学附属北京地坛医院感染中心,北京 100015
- 折叠
摘要
人偏肺病毒属于副粘病毒科,肺病毒亚科,偏肺病毒属,为有包膜的单链负RNA病毒.能够引起各年龄段人群感染,多表现为轻度自限性疾病.在免疫功能低下人群中可进展为重症肺炎、多器官功能衰竭,甚至导致死亡.主要通过呼吸道和接触传播,主要依靠核酸检测确诊,无特异性的抗病毒药物,主要以支持治疗为主.尚无疫苗上市.
Abstract
Human metapneumovirus,a single stranded negative RNA virus with an envelope,belongs to the family Pa-ramyxoviridae,subfamily Pneumoviruses,and genus Polypneumovirus.It often causes infections among the population of all age groups,most of the population manifest as mild self-limiting diseases,which may progress to severe pneumonia,multiple organ failure and even lead to death among the immunocompromised population.The respiratory tract and con-tact were the major transmission routes,nucleic acid test was the major diagnostic mean.There are no specific antiviral drugs,and supportive treatment is dominant.There has not been vaccine available yet.
关键词
人偏肺病毒/感染/病原学/流行病学/发病机制/临床表现/诊断和治疗Key words
Human metapneumovirus/Infection/Etiology/Epidemiology/Pathogenesis/Clinical manifestation/Diagnosis and treatment引用本文复制引用
基金项目
2022年北京市高层次公共卫生技术人才建设项目(学科带头人-01-02)
出版年
2024