Association of serum CK and LDH with age of patients with COVID-19 Omicron variant infection
OBJECTIVE To investigate the correlation of serum creatine kinase and lactate dehydrogenase with age inpatients with pneumonia infected by Omicron variant of novel coronavirus infection 2019(COVID-19).METHODS A total of 226 patients with COVID-19 Omicron variant infection diagnosed in No.988 Hospital of the joint Logistics Support Force of PLA from Oct.16 to Dec.31,2022 were selected as the infection group,and 247 new crown nucleic acid-negative patients hospitalized in the same department during the same period with infec-tious phases but not infected with COVID-19 Omicron variant were selected as the control group,and the clinical data and laboratory tests were collected from both group.Clinical characteristics such as gender,age distribution,and laboratory indicators of CK and LDH were analyzed in both groups.RESULTS There was no statistically sig-nificant difference in the gender composition and age distribution of the patients in the two groups.Compared with the control group,level and abnormal increase of serum CK were elevated in the total population of the infected group(P＜0.05),with the elevated CK level being most significant in the elderly(≥60),young adults(16 year-s-)and young children(1 year-)(P＜0.05),and the elevated LDH level and abnormal increase being most sig-nificant in young children(1 year-)(P＜0.05).CONCLUSION Elevated CK in COVID-19 Omicron variant-infec-ted patients was predominantly found in the elderly and young adult and young children patients,whereas elevated LDH was more common in young children,which might provide references for the development of a targeted ther-apeutic regimen.
Coronavirus disease 2019Omicron variantCreatine kinaseLactate dehydrogenaseThe elderlyYoung children
NETL
NSTL
万方数据
