首页|血液透析患者中心静脉导管相关血流感染病原菌及其危险因素

血液透析患者中心静脉导管相关血流感染病原菌及其危险因素

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目的 探讨血液透析患者中心静脉导管相关血流感染(CLABSI)病原菌及其危险因素。方法 回顾性选取2019年1月—2022年12月苏州市第九人民医院收治的327例血液透析患者为研究对象,根据CLABSI情况分为感染组(26例)和非感染组(301例);统计血液透析患者中心静脉导管相关血流感染病原菌,分析两组患者的临床资料,归纳血液透析患者CLABSI的危险因素。结果 血液透析患者中心静脉导管相关血流感染发生率为7。95%(26/327);病原菌分布中以革兰阳性菌为主;Logistic回归分析发现,年龄和导管留置时间是血液透析患者CLABSI的危险因素(OR=1。970、2。298,P均<0。05)。结论 血液透析患者CLABSI发生率较高,病原菌分布中以革兰阳性菌居多;血液透析患者中心静脉导管相关血流感染与年龄、导管留置时间密切相关;临床可据此给予患者针对性治疗及预防措施,以降低血液透析患者CLABSI的风险。
Pathogenic bacteria of central venous catheter-related bloodstream infection and their risk factors in hemodialysis patients
OBJECTIVE To investigate the pathogenic bacteria of central venous catheter-related bloodstream infec-tions(CLABSI)and their risk factors in hemodialysis patients.METHODS Totally 327 hemodialysis patients ad-mitted to the Ninth People's Hospital of Suzhou from Jan.2019 to Dec.2022 were retrospectively selected as the research subjects,and were divided into the infected group(26 cases)and the non-infected group(301 cases)ac-cording to whether central venous catheter-related bloodstream infection occurred.The pathogenic bacteria of cen-tral venous catheter-related bloodstream infection in hemodialysis patients were analyzed,the clinical data of the two groups of patients were analyzed,and the risk factors of central venous catheter-related bloodstream infection in hemodialysis patients were summarized.RESULTS The incidence of central venous catheter-related bloodstream infection in hemodialysis patients was 7.95%(26/327).Gram-positive bacteria predominated in the distribution of pathogenic organisms.Multivariate Logistic regression analysis showed that age and catheter retention time were the risk factors for central venous catheter-related bloodstream infection in hemodialysis patients(OR=1.970,2.298,P<0.05).CONCLUSION The incidence of central venous catheter-associated bloodstream infection in he-modialysis patients was high,and gram-positive bacteria were the main pathogens.Central venous catheter-related bloodstream infection in hemodialysis patients was closely related to patient age and catheter indwelling time.Therefore,targeted treatment and preventive measures could be taken to reduce the risk of central venous cathe-ter-related bloodstream infection in hemodialysis patients.

HemodialysisCentral venous catheterBloodstream infectionPathogenRisk factorPreventive measure

沈瑜、宋晓莉、张欢茜

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苏州市第九人民医院血液透析室,江苏苏州 215200

血液透析 中心静脉导管 血流感染 病原菌 危险因素 预防措施

苏州市第九人民医院院级科研启动基金立项合同

YK202224

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(4)
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