首页|胸腔镜肺叶切除患者术后感染病原菌及其危险因素

胸腔镜肺叶切除患者术后感染病原菌及其危险因素

扫码查看
目的 探讨胸腔镜肺叶切除患者术后肺部感染病原菌及其危险因素。方法 选择2019年1月—2022年12月于成都大学附属医院实施胸腔镜肺叶切除术治疗的肺癌患者327例为研究对象,并根据术后肺部感染情况分为感染组(n=38)和未感染组(n=289),分析感染组患者肺部病原菌情况,归纳胸腔镜肺叶切除患者术后肺部感染的危险因素。结果 肺部感染患者总共培养分离病原菌54株,其中革兰阳性菌22株占40。74%,革兰阴性菌28株占51。85%,真菌4株占7。41%,以铜绿假单胞菌、肺炎克雷伯菌以及金黄色葡萄球菌为主;糖尿病(OR=1。880)、慢性阻塞性肺病(OR=2。343)、手术时间(OR=2。161)是胸腔镜肺叶切除患者术后肺部感染的危险因素(P<0。05)。结论 糖尿病、慢性阻塞性肺病、手术时间是胸腔镜肺叶切除患者术后肺部感染的危险因素,且感染病原菌以革兰阴性菌为主,临床应针对高危人群及感染病原菌种类进行有效预防和治疗。
Postoperative infectious pathogens in patients undergoing thoracoscopic lobectomy and their risk factors
OBJECTIVE To investigate the postoperative infectious pathogens in patients undergoing thoracoscopic lobectomy and their rick factors.METHODS Totally 327 lung cancer patients who underwent thoracoscopic lobec-tomy at the Affiliated Hospital of Chengdu University from Jan.2019 to Dec.2022 were selected as the study subjects,and they were divided into the infection group(n=38)and the non-infection group(n=289)according to postoperative pulmonary infection,and the lung pathogens in the patients of the infection group were analyzed,and the risk factors of postoperative pulmonary infection in patients undergoing thoracoscopic lobectomy were summarized.RESULTS A total of 54 strains of pathogenic bacteria were cultured and isolated from patients with pulmonary infections,of which 22 strains of gram positive bacteria accounted for 40.74%,28 strains of Gram negative bacteria accounted for 51.85%,and 4 strains of fungi accounted for 7.41%,with Pseudomonas aerugi-nosa,Klebsiella pneumoniae,and Staphylococcus aureus being the predominant strains.The combination of dia-betes mellitus(OR=1.880),chronic obstructive pulmonary disease(OR=2.343),and the duration of operation(OR=2.161)were risk factors for postoperative pulmonary infection in patients undergoing thoracoscopic lobec-tomy(P<0.05).CONCLUSION Diabetes mellitus,chronic obstructive pulmonary disease,and duration of oper-ation were risk factors for postoperative pulmonary infection in patients undergoing thoracoscopic lobectomy,and the infectious bacteria were mainly gram-negative bacteria.Clinical prevention and treatment should be targeted for the high-risk groups and the type of infectious pathogens.

Thoracoscopy lobectomyPathogenic bacteriaPulmonary infectionPostoperative infectionRisk factor

刘丽、樊新星、苏东辉、熊健

展开 >

成都大学附属医院胸心血管甲乳外科,四川成都 610081

成都大学附属医院西药剂科,四川成都 610081

厦门市第五医院胸外科,福建厦门 361000

成都大学附属医院骨科,四川成都 610081

展开 >

胸腔镜肺叶切除术 病原菌 肺部感染 术后感染 危险因素

四川省医学会基金资助项目

2022SAT02

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(4)
  • 26