首页|保妇康栓治疗宫颈HPV感染的疗效

保妇康栓治疗宫颈HPV感染的疗效

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目的 探究保妇康栓治疗宫颈人乳头瘤病毒(HPV)感染的疗效及其HPV转阴率。方法 选取2020年2月—2021年2月于遵义市第一人民医院就诊的64例宫颈HPV病毒感染患者为研究对象,随机分为保妇康栓组(保妇康栓治疗)和干扰素栓组(干扰素栓治疗)各32例,对干预效果进行分析比较。结果 保妇康栓组疗效优于干扰素栓组(P<0。05);用药前两组各项指标差异无统计学意义,用药后保妇康栓组CD3+、CD4+、CD4+/CD8+高出干扰素栓组,但CD8+低于干扰素栓组(P<0。05);用药后保妇康栓组白带脓性、白带量异常、宫颈糜烂积分均低于干扰素栓组(P<0。05);用药后保妇康栓组IL-2、IL-1β低于干扰素栓组(P<0。05);保妇康栓组研究对象HPV转阴率高于干扰素栓组(P<0。05)。结论 宫颈HPV感染患者采用保妇康栓治疗,效果更为理想,同时能提升高危型HPV转阴率,能快速促进炎性反应缓解,调节免疫功能,减轻症状。
Effect of Baofukang suppository on treatment of cervical HPV infection
OBJECTIVE To investigate the curative effect of Bafukang suppository in the treatment of cervical hu-man papillomavirus(HPV)infection and its HPV conversion rate.METHODS Totally 64 cases of cervical HPV infection patients treated in the First People's Hospital of Zunyi City from Feb.2020 to Feb.2021 were selected as the study subjects,and randomly divided into Bafukang supposal group(Bafukang supposal treatment)and in-terferon supposal group(interferon supposal treatment),with 32 cases in each group,and the effect of the inter-vention was analyzed and compared.RESULTS The curative effect of Bafukang Supposal group was better than that of interferon supposal group(P<0.05).There was no significant difference in the indicators between the two groups before treatment.After treatment,the CD3+,CD4+and CD4+/CD8+in Bafukang supposer group were higher than those in interferon supposer group,while the CD8+was lower than that in interferon supposer group(P<0.05).After treatment,the pyorrhea,abnormal amount of leucorrhea and cervical erosion scores in Bafukang supposal group were lower than those in interferon supposal group(P<0.05).The levels of IL-2 and IL-1β in Bafukang supposal group were lower than those in interferon supposer group(P<0.05).The HPV con-version rate of Baofukang suppository group was higher than interferon suppository group(P<0.05).CONCLUSION The effect of Baofukang supposal in treating patients with cervical HPV infection was more effec-tive,and at the same time it could enhance the rate of high-risk HPV conversion,and quickly promote the relief of inflammatory reactions,regulate immune function,and alleviate the symptoms.

Interferon suppositoryHuman papillomavirusBaofukang suppositoryNegative conversion rate

田静、周登艳、刘志霞、张金波、张颖

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遵义市第一人民医院妇产科,贵州遵义 563000

干扰素栓 人乳头瘤病毒 保妇康栓 转阴率

遵义市科技计划项目

遵市科合HZ202268号

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(4)
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