Etiological and epidemiological characteristics of hand-foot-mouth disease in 576 children of a hospital in Huai'an from 2020 to 2022
OBJECTIVE To investigate the epidemiology of hand-foot-mouth disease in a hospital of Huaian City,2020-2022.METHODS Clinical data of 232 children with hand-foot-mouth disease admitted to the Huaian Mater-nal and Child Health Hospital from Jan.2020 to Dec.2022 were retrospectively collected.All the children were confirmed by viral nucleic acid detection.The etiological composition,gender,occupation,age of onset,and time distribution of onset were analyzed.RESULTS From 2020 to 2022,the percentage of Coxsackievirus A16(CA16)and Enterovirus 71(EV71)infections were 80.00%,50.50%,62.75%and 20.00%,49.50%and 37.25%,re-spectively,with a three-year total of 63.36%and36.64%,respectively.The gender distribution was mainly dis-tributed in males,with a percentage of 58.75%,55.45%and 54.90%respectively,with a three-year total of 56.47%.The occupational distribution was mainly among scattered children,with 61.25%,51.49%and 62.75%,respectively,with a three-year total of 57.33%.The students had the least percentage,with 6.25%,5.94%and 5.88%,respectively,and the a three-year total of 6.03%.The age of onset was mainly distributed in 0-,1-and 2-years,accounting for 32.50%,30.00%,18.75%,31.68%,28.71%,20.79%,33.33%,27.45%and 21.57%,respectively,with a total three-year percentage of 32.33%,28.88%and 20.26%,respec-tively.The time of onset of the disease were all mainly distributed in the second quarter,accounting for 81.25%,79.21%and 80.39%,respectively,with a three-year total of 80.17%.CONCLUSION From 2020 to 2022,chil-dren with hand-foot-mouth disease in a hospital in Huai an city were mainly infected with CA16,and males,scat-tered children,and children aged 0-,1-,and 2-were more susceptible to the disease,and the main epidemic season was the second quarter,so clinical intervention could be tailored to the above characteristics to reduce the risk of hand-foot-mouth disease in the children concerned.