Clinical characteristics of 40 hospitalized children with type A influenza virus in Kashgar region,Xinjiang,China
OBJECTIVE To investigate the clinical characteristics of hospitalized children with type A influenza virus post-epidemic.METHODS Clinical data of 40 hospitalized children with influenza A virus confirmed by influenza virus nucleic acid testing at the 947th Hospital of Army during the period from Feb.to Jun.2023 were collected and analyzed.RESULTS The onset age was from 3 months to 12 years old,with a median age of 4 years old,of which 28 cases(70.00％)were aged 0 to 5 years,with spring being the peak of the onset of the disease.Fever and cough were the main clinical manifestations.Comorbidities included pneumonia in 24 cases(60.00％),inclu-ding 28 cases(70.00％)in children aged 0-5 years,with a significant difference compared to those aged 6-12 years(12 case,30.00％)(P＜0.05),acute laryngitis in 2 cases,myocardial injury in 5 cases,febrile convulsion in 3 cases,electrolyte disorders in 2 cases,myositis in 1 case,and severe sepsis in 1 case.There were 30 cases(75.00％)of single influenza virus infection,and 10 cases(25.00％)of mixed infection,including 4 cases of my-coplasma infection and 6 cases of bacterial infection.Thirty-two children were given oseltamivir granules orally,of which 11 cases were given within 48 h of fever and 21 cases were given after 48 h.The fever time and hospitaliza-tion time in the group given oseltamivir granules within 48 h were lower than those in the group given medicine af-ter 48 h.All children were cured.CONCLUSION The majority of hospitalized children with influenza virus type A were children under 5 years old.The symptoms were non-specific,with high fever and cough as the main manifes-tations,and multiple comorbidities might occur,with pneumonia being the most common.Children infected with influenza A might have a mixture of other pathogenic infections.Early diagnosis and treatment generally had a good prognosis.
Type A influenza virusPneumoniaChildrenClinical characteristics
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