Risk factors for pneumonia in children with Epstein-Barr virus-associated infectious mononucleosis
OBJECTIVE To investigate the risk factors for pneumonia complication in children with human herpes-virus(EB)virus-induced infectious mononucleosis(IM).METHODS The clinical data of 187 children with Ep-stein-Barr viruse-induced IM admitted to Suzhou Hi-Tech District People's Hospital from Mar.2020 to Mar.2023 were retrospectively analyzed,and the children were divided into 55 cases of pneumonia group and 132 cases of non-pneumonia group according to whether they were complicated with pneumonia.The clinical data of the two groups were compared,and the risk factors for pneumonia in children with IM caused by Epstein-Barr virus.RESULTS The levels of C-reactive protein(CRP),procalcitonin(PCT)and neutrophil/lymphocyte(NLR)in pneumonia group were higher than those in non-pneumonia group(P＜0.05).Multivariate Logistic regression a-nalysis showed that older age,hepatosplenomegaly and long duration of fever were risk factors for pneumonia complication in children with Epstein-Barr viruse-induced IM(OR=2.109,2.079,1.972,P＜0.05).CONCLUSION Serum CRP,PCT and NLR were highly expressed in children with Epstein-Barr virus IM compli-cated with pneumonia.Clinical prevention and intervention measures could be given according to risk factors to re-duce the risk of pneumonia in children with Epstein-Barr viruse-induced IM.
Infectious mononucleosisEB virusPneumoniaRisk factorPrevention and control measures
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