Etiological characteristics,drug resistance and risk factors for urinary tract infection in type 2 diabetes mellitus patients
OBJECTIVE To explore the etiological characteristics,drug resistance and risk factors for urinary tract infection in the patients with type 2 diabetes mellitus(T2DM).METHODS The clinical data were collected from 272 patients with T2DM who were treated in Yingtan People's Hospital from Mar 2020 to Mar 2023.The patients who had urinary tract infection were assigned as the infection group,and 219 patients who did not have urinary tract infection were assigned as the non-infection group.The prevalence of urinary tract infection among the T2DM patients,distribution and drug resistance of pathogens were statistically analyzed.Logistic analysis was performed for the risk factors for the urinary tract infection in the T2DM patients.RESULTS Among the 272 patients with T2DM,53 had urinary tract infection,accounting for 19.49％.Totally 55 strains of pathogens were isolated from the 53 patients of the infection group,39(70.91％)of which were gram-negative bacteria,Escherichia coli was dominant among the gram-negative bacteria;the gram-positive bacteria accounted for 25.45％(14 strains);the fungi accounted for 3.64％(2 strains).The result of drug susceptibility testing showed that the E.coli was highly resistant to ampicillin and levofloxacin but was highly sensitive to imipenem and tigecycline.The more than 60 years of age,course of T2DM more than 10 years,urinary catheter indwelling,high level of fasting blood glucose(FBG)and high level of glycosylated hemoglobin(HbAlc)were the risk factors for the urinary tract infection in the T2DM patients(P＜0.05).CONCLUSION The incidence of urinary tract infection is high among the patients with T2DM.The major species of gram-negative bacteria E.coli is highly sensitive to imipenem and tigecycline.The urinary tract infection in the T2DM patients is associated with the age,course of T2DM,urinary catheter in-dwelling,FBG level and HbAlc level.It is necessary for the hospital to take targeted prevention and treatment measures in early stage based on the risk factors.
Type 2 diabetes mellitusUrinary tract infectionEscherichia coliDrug resistanceRisk factor
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