Risk factors for nosocomial infections in ICU patients and establishment of nomogram model
OBJECTIVE To explore the risk factors for nosocomial infection in the patients of intensive care units(ICUs)of three general hospitals in Guizhou Province and establish a visualized nomogram model.METHODS A total of 850 patients who were treated in comprehensive ICUs of Guizhou Provincial People's Hospital,Guizhou Provincial Second People's Hospital and Keichow Moutai Hospital from May 24,2022 to May 24,2023 were re-cruited as the research subjects,266 of whom had nosocomial infection,and 584 did not have nosocomial infection.The risk factors for the nosocomial infection were identified by using binary logistic regression model,the visual-ized nomogram model was established based on the risk factors,and the differentiating performance of the model was validated by means of receiver operating characteristic(ROC)curves.RESULTS Among the 850 patients,266(31.3％)had nosocomial infection.The major risk factors for the nosocomial infection included the male,long length of hospital stay,many time of abnormal submission of blood routine test,many times of abnormal submis-sion of procalcitonin,stay of non-ICU departments,many times of isolation of multidrug-resistant organisms and long-term use of ventilator.The risk probability of nosocomial infection in the ICU patients could be directly calcu-lated by the nomogram model that was established based on the risk factors,and the model has significant differ-entiating value,with the area under curve 0.872.CONCLUSION The nomogram model that is established based on the risk factors for the nosocomial infection in the ICU patients of Guizhou Province can quantify the risk factors so as to take more effective coping measures and further reduce the incidence of nosocomial infection.
Intensive care unitNosocomial infectionRisk factorNomogramModelRetrospective study
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