Investigation and analysis of prevalence rates of nosocomial infection in a tertiary grade-A general hospital from 2013 to 2022
OBJECTIVE To analyze the current situation and trend of nosocomial infection in in a tertiary grade-A general hospital in Shandong Province for 10 consecutive years,and find out the problems of nosocomial infection prevention and control,so as to provide evidence for the scientific prevention and control.METHODS A cross-sec-tional survey was conducted on all hospitalized patients in the People's Hospital of Rizhao on survey days from 2013 to 2022,and SPSS 25.0 statistical software was used to analyze the data.RESULTS A total of 17 848 inpa-tients from 2013 to 2022 were investigated,and 444 person-times and 457 cases of nosocomial infection oc-curred.The current case rate fluctuated between 2.03%and 3.48%.There was no significant difference in the cur-rent case rate of hospital infection among different years(x2=14.570,P=0.103).The main site of nosocomial infection was lower respiratory tract,accounting for 61.84%on average.There was no significant difference in the distribution of infection sites among different years(H=1.307,P=0.998);The main pathogens of infection were gram-negative bacteria(172),accounting for 69.92%,mainly including Klebsiella pneumoniae.Acineto-bacter baumannii,Escherichia coli and Pseudomonas aeruginosa.The antibiotic use rate was 27.18%,with a trend of increasing year by year.The antibacterial drugs was used mainly in single-agent therapy.The rate of pathogen examination before administration of antibacterial drugs was 59.50%.The difference in the rate of patho-gen examination before treatment of antibacterial drugs in different years was statistically significant(x2=24.970,P=0.003).CONCLUSION The overall prevalence rate of nosocomial infection in the hospital is relatively stable,and the rate of pathogenic examination before the use of antibacterial drugs is increasing year by year.The rational use of antibacterial drugs is still the focus of nosocomial infection control at this stage.
Prevalence rateNosocomial infectionAntimicrobial drugsPathogenHospital infection prevention and control