Systemic immune-inflammation indexes,peripheral blood NLR,RDW and PLR of cerebral infarction patients complicated with pulmonary infection and assessment of prognosis
OBJECTIVE To analyze the correlation of systemic immune-inflammation index(SII),peripheral blood neutrophil to lymphocyte ratio(NLR),red cell distribution width(RDW)and platelet to lymphocyte ratio(PLR)with pulmonary infection after cerebral infarction,and to evaluate the predictive value of the above indexes on prognosis of patients.METHODS A total of 80 patients with pulmonary infection after cerebral infarction admitted to Tongling People's Hospital in Anhui Province from Jun 2020 to Aug 2023 were recruited,and 80 patients with cerebral infarction in the hospital during the same period were included in the control group.The patients in the study group were subdivided into the poor prognosis group and good prognosis group according to modified rankin scale scores in patients after three months.Levels of SII,NLR,RDW and PLR among groups were compared,and the risk factors of pulmonary infection after cerebral infarction were analyzed by multivariate logistic analysis.Receiver operating characteristic(ROC)curve and area under the curve(AUC)were used to evaluate the diagnos-tic value of SII,NLR,RDW and PLR on pulmonary infection after cerebral infarction and predictive value on prognosis.RESULTS Levels of SII,NLR,RDW and PLR in the study group were higher than those in the control group(P＜0.05).Age,invasive procedure,swallowing dysfunction,NIHSS score,SII,NLR,RDW and PLR were the risk factors for pulmonary infection after cerebral infarction(P＜0.05).The AUC values of SII,NLR,RDW,PLR individual and combined detection in the diagnosis of pulmonary infection after cerebral infarction were 0.839,0.853,0.839,0.876 and 0.975,respectively.The SII,NLR,RDW and PLR levels in the poor prognosis group were higher than those in the good prognosis group(P＜0.05).The AUC values of SII,NLR,RDW,PLR alone and the combination in predicting the prognosis of patients with pulmonary infection after cerebral infarction were 0.702,0.687,0.681,0.678 and 0.792,respectively.CONCLUSION The SII,NLR,RDW and PLR levels in patients with pulmonary infection after cerebral infarction increase,which can affect the prognosis of the patients.Patients with old age,invasive procedure,swallowing dysfunction and high NIHSS score should be considered in clinic treatment.
Systemic immune-inflammatory indexNeutrophil to lymphocyte ratioRed cell distribution widthPlatelet to lymphocyte ratioCerebral infarctionPulmonary infectionPrognosis
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