Nosocomial infection monitoring data and trend analysis of orthopedic inpatients in a tertiary orthopedic hospital from 2019 to 2022
OBJECTIVE To investigate current situation of nosocomial infection among orthopaedic inpatients in Wuxi Orthopedic Hospital from 2019 to 2022.METHODS Through the electronic medical record management platform and the real-time monitoring system for hospital infection,the hospital infection status of orthopedic in-patients from 2019 to 2022,the distribution of infection sites,the distribution of main infectious pathogens,and the drug resistance of main pathogens were analyzed.RESULTS From 2019 to 2022,among 68 792 orthopedic in-patients,1 072 cases of hospital infections occurred,with a hospital infection rate of 1.56%,and hospital infec-tions occurred in 1 161 admissions,with an infection rate of 1.69%.The hospital infection rate and case infection rate of orthopedic inpatients from 2020 to 2022 decreased as compared with 2019.And the hospital infection rate and case infection rate in 2020 and 2022 were lower than those in 2021(P<0.05).From 2019 to 2022,the top three nosocomial infections and infection patients in orthopedic departments were hand surgery,trauma orthope-dics and foot and ankle surgery.From 2019 to 2022,the top three most common infection sites of orthopedic inpa-tients were surgical sites,skin and soft tissues,and lower respiratory tract.Escherichia coli and Acinetobacter baumannii accounted for the highest proportion of gram-negative bacteria,while Staphylococcus aureus and Staphylococcus epidermidis accounted for the highest proportion of gram-positive bacteria.E.coli had a high drug-resistant rate to ampicillin,piperacillin,and cefuroxime,while A.baumannii had a high drug-resistant rate to cefuroxime,cefazolin,and ceftazidime.S.aureus had a high drug-resistant rate to cefoxitin,penicillin,and clindamycin,while it was sensitive to vancomycin and teicoplanin.S.epidermidis had a high drug-resistant rate to erythromycin,cefoxitin,penicillin,oxacillin and clindamycin,while it was sensitive to vancomycin.CONCLUSION Hospitals should take timely and effective prevention and control measures based on bacteria distri-bution in orthopedic departments,major infection sites,the types of major infectious pathogens and drug resist-ance status to reduce the nosocomial infection rate in orthopedic inpatients.
OrthopedicsInpatientHospital infectionDistribution of infectionPathogenic bacteriaDrug re-sistance