Etiological characteristics and risk factors for postoperative intracranial infection in cerebral aneurysm patients undergoing clipping surgery
OBJECTIVE To explore the etiological characteristics and risk factors for postoperative intracranial in-fection in the cerebral aneurysm patients undergoing clipping surgery.METHODS The clinical data were collected from 370 cerebral aneurysm patients who underwent clipping surgery in Tianjin Huanhu Hospital from Jan 2019 to May 2023 and were retrospectively analyzed.51 patients were complicated with intracranial infection and were as-signed as the infection group,and 319 patients were not complicated with intracranial infection and were assigned as the no infection group.The etiological characteristics and risk factors for the postoperative intracranial infection in the cerebral aneurysm patients were observed.RESULTS Of the 370 cerebral aneurysm patients who underwent clipping surgery,51 were complicated with intracranial infection,with the infection rate 13.78％.Totally 44 strains of pathogens were isolated,27(61.36％)of which were gram-positive bacteria,and 17(38.64％)were gram-negative bacteria;Staphylococcus hominis was the predominant species of gram-positive bacteria,and Kleb-siella pneumoniae was dominant among the gram-negative bacteria.Intraoperative blood loss volume more than 100ml,lumbar cerebrospinal fluid drainage,external ventricular drainage,drainage tube indwelling time and length of hospital stay were the independent risk factors for the postoperative intracranial infection in the cerebral aneurysm patients undergoing clipping surgery(P＜0.05).CONCLUSION S.homonis and K.pneumoniae are the predominant species of pathogens isolated from the cerebral aneurysm patients with intracranial infection after the clipping surgery.The risk factors for the postoperative intracranial infection include the intraoperative blood loss volume more than 100ml,lumbar cerebrospinal fluid drainage,external ventricular drainage,drainage tube in-dwelling time and length of hospital stay.It is necessary for the hospital to take targeted prevention and treatment measures so as to reduce the risk of postoperative intracranial infection in the cerebral aneurysm patients undergo-ing clipping surgery.
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