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妊娠晚期生殖道B族链球菌感染危险因素及其妊娠结局

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目的 探究妊娠晚期生殖道B族链球菌(GBS)感染情况和危险因素及其妊娠结局。方法 回顾性分析282例2022年1月-2022年12月杭州市妇产科医院接收的妊娠晚期孕妇临床资料,根据生殖道是否发生GBS感染分为GBS感染组42例和非GBS感染组240例,分析妊娠晚期孕妇发生生殖道GBS感染的危险因素及其对妊娠结局的影响。结果 282例妊娠晚期孕妇发生生殖道GBS感染42例,发生率为14。89%;年龄≥35岁、有阴道炎、有糖尿病均为妊娠晚期孕妇发生生殖道GBS感染的独立危险因素(OR=2。375、2。042、2。210,P<0。05);42例GBS感染孕妇依据GBS定植量分为24例高定植量和18例低定植量,GBS高定植量孕妇早产、剖宫产和绒毛膜羊膜炎发生率高于GBS低定植量孕妇(P<0。05)。结论 妊娠晚期孕妇生殖道GBS感染的发生率较高,妊娠晚期孕妇发生生殖道GBS感染的危险因素包括年龄≥35岁、有阴道炎、有糖尿病,GBS高定植量孕妇对不良妊娠结局有较大的影响。临床可据此给予孕妇针对性治疗及干预措施,以降低妊娠晚期孕妇发生生殖道GBS感染的风险。
Risk factors for genital tract group B Streptococcus infection in pregnant women of late trimester of pregnancy and pregnancy outcomes
OBJECTIVE To explore the prevalence and risk factors for the genital tract group B Streptococcus(GBS)infection in the pregnant women of late trimester of pregnancy and analyze the pregnancy outcomes.METHODS The clinical data were collected from 282 pregnant women of late trimester of pregnancy who were treated in Hangzhou Obstetrics and Gynecology Hospital from Jan 2022 to Dec 2022 and were retrospectively ana-lyzed.The pregnant women were divided into the GBS infection group with 42 cases and the non-GBS infection group with 240 cases according to the status of genital tract GBS infection.The risk factors for the genital tract GBS infection and the influence on pregnancy outcomes were observed.RESULTS Among the 282 pregnant women of late trimester of pregnancy,42 had genital tract GBS infection,with the incidence 14.89%.No less than 35 years of age,vaginitis and diabetes mellitus were the independent risk factors for the genital tract GBS infection(OR=2.375,2.042,2.210,P<0.05).The 42 pregnant women with GBS infection were divided into 24 cases of high colonization amount and 18 cases of low colonization amount according to the colonization amount of GBS.The incidence rates of premature delivery,cesarean section and chorioamnionitis were significantly higher among the pregnant women with high colonization amount of GBS than among the pregnant women with low colonization amount of GBS(P<0.05).CONCLUSION The incidence of genital tract GBS infection is high among the pregnant women of late trimester of pregnancy.The influencing factors for the genital tract GBS infection include the no less than 35 years of age,vaginitis and diabetes mellitus.The high colonization amount of GBS has great impact on the adverse pregnancy outcomes.It is necessary for the hospital to take targeted treatment and intervention measures so as to reduce the risk of genital tract GBS infection in the pregnant women of late trimester of pregnancy.

Late trimester of pregnancyPregnant womanGenital tract group B Streptococcus infectionRisk factorPregnancy outcome

施锦金、蔡锋成、张晶、郑敏珠、潘燕

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杭州市妇产科医院分娩中心,浙江杭州 310000

妊娠晚期 孕妇 生殖道B族链球菌感染 危险因素 妊娠结局

浙江省医药卫生科技计划

2023KY996

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(9)
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