首页|老年慢性心力衰竭合并糖尿病患者发生肺部感染的危险因素及其预测模型构建

老年慢性心力衰竭合并糖尿病患者发生肺部感染的危险因素及其预测模型构建

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目的 分析老年慢性心力衰竭(CHF)合并糖尿病患者发生肺部感染的危险因素及其风险模型构建。方法 选取2020年1月-2022年6月衡水市人民医院收治的126例老年CHF合并糖尿病患者,根据是否发生肺部感染分为感染组(26例)和未感染组(100例),对比两组临床资料及实验室检查结果,采用多因素Logistic回归分析患者并发肺部感染的危险因素并构建预测模型,绘制受试者工作特征(ROC)曲线分析模型对患者并发肺部感染的诊断价值。结果 两组患者年龄、住院时间、长期卧床、高血压史、吸烟史、合并慢性阻塞性肺疾病和侵入性操作比较有统计学差异(P<0。05);多因素Logistic逐步回归分析显示,年龄(OR=3。418,95%CI:1。895~6。165)、长期卧床(OR=3。059,95%CI:1。823~5。132)、侵入性操作(OR=4。225,95%CI:2。062~8。657)均为老年CHF合并糖尿病患者并发肺部感染的危险因素(P<0。05);根据筛选的危险因素构建的预测模型,绘制ROC曲线结果显示,模型预测老年CHF合并糖尿病患者并发肺部感染的曲线下面积(AUC)为0。801,95%CI为0。751~0。851。结论 年龄、长期卧床、侵入性操作均是老年CHF合并糖尿病患者并发肺部感染的危险因素,构建的风险预测模型对肺部感染具有良好的预测价值。
Risk factors for pulmonary infection in elderly chronic heart failure patients complicated with diabetes mellitus and establishment of prediction model
OBJECTIVE To investigate the risk factors for pulmonary infection in the elderly chronic heart failure(CHF)patients complicated with diabetes mellitus and establish the risk model.METHODS A total of 126 elderly CHF patients complicated with diabetes mellitus who were treated in Hengshui People's Hospital from Jan 2020 to Jun 2022 were enrolled in the study and were divided into the infection group with 26 cases and the no infection group with 100 cases according to the status of pulmonary infection.Multivariate logistic regression analysis was performed for the risk factors for the pulmonary infection,the prediction model was established,and the value of the model in diagnosis of the pulmonary infection was analyzed by means of receiver operating characteristic(ROC)curves.RESULTS There were significant differences in the age,length of hospital stay,long bedridden,history of hypertension,smoking history,complication with chronic obstructive pulmonary disease and invasive procedures between the two groups of patients(P<0.05).Multivariate logistic stepwise regression analysis indica-ted that age(OR=3.418,95%CI:1.895-6.165),long bedridden(OR=3.059,95%CI:1.823-5.132)and invasive procedures(OR=4.225,95%CI:2.062-8.657)were the risk factors for the pulmonary infection in the eldelry CHF patients complicated with diabetes mellitus(P<0.05).The prediction model was established based on the screened risk factors,and the result of ROC curve analysis showed that the area under curve(AUC)of the model was 0.801 in prediction of the pulmonary infectionin the elderly CHF patients complicated with diabetes mellitus,with the 95%CI 0.751-0.851.CONCLUSION The age,long bedridden time and invasive procedures are the risk factors for the pulmonary infection in the elderly CHF patients complicated with diabetes mellitus.The established risk prediction model has high value in prediction of pulmonary infection.

The elderlyChronic heart failureDiabetes mellitusPulmonary infectionRisk factorPrediction model

马佳佳、李勇、高肖坤、王琼、刘琛

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衡水市人民医院心血管内科,河北衡水 053000

老年 慢性心力衰竭 糖尿病 肺部感染 危险因素 预测模型

河北省卫生健康委医学科学研究课题

20232165

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(10)
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