首页|2020-2022年呼和浩特市某哨点监测医院5岁以下儿童腹泻监测报告

2020-2022年呼和浩特市某哨点监测医院5岁以下儿童腹泻监测报告

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目的 分析呼和浩特市5岁以下儿童病毒性腹泻的常见病原体及流行病学特征,以采取有效的防控措施.方法 收集2020年1月1日-2022年12月31日内蒙古自治区妇幼保健院5岁以下因腹泻住院儿童的粪便标本与个案信息,采用实时逆转录聚合酶链反应(RT-PCR)和酶联免疫吸附试验(ELISA)检测方法对粪便进行轮状病毒、诺如病毒、札如病毒、肠道腺病毒等可引发病毒性腹泻的主要病原体检测,并利用统计学方法对监测结果进行分析.结果 526份5岁以下腹泻住院儿童粪便标本中,110份标本检出轮状病毒、诺如病毒、札如病毒、肠道腺病毒,总检出率为21.10%,其中,轮状病毒检出率为7.80%,诺如病毒检出率为10.46%,札如病毒检出率为0.95%,腺病毒检出率为1.90%;诺如病毒检出率存在性别差异(x2=3.869,P=0.049);除腺病毒外,不同年份轮状病毒(x2=14.209,P<0.001)、诺如病毒(x2=13.555,P<0.001)和札如病毒(x2=6.376,P=0.024)检出率比较差异具有统计学意义.结论 轮状病毒、诺如病毒是呼和浩特地区5岁以下儿童病毒性腹泻主要病原体,感染高峰期易出现在寒冷季节,多发于>10~≤20月龄段,诺如病毒男童病毒检出率高于女童.
Monitoring of prevalence of diarrhea among children aged less than 5 years old in a sentinel monitoring hospital of Hohhot from 2020 to 2022
OBJECTIVE To investigate the common species of pathogens isolated from the viral diarrhea children aged less than 5 years old in Hohhot and analyze the epidemiological characteristics so as to take effective preven-tion measures.METHODS The stool samples and individual information were collected from the children aged less than 5 years old who were hospitalized in Inner Mongolia Maternal and Child Health Care Hospital due to diarrhea from Jan 1,2020 to Dec 31,2022.The major pathogens such Rotavirus,Norovirus,Sapovirus and Adenovirus that may cause the viral diarrhea were detected by means of real-time reverse transcription polymerase chain reac-tion(RT-PCR)and enzyme-linked immunosorbent assay(ELISA).The result of monitoring was statistically ana-lyzed.RESULTS Among 526 stool samples that were collected from the hospitalized children with diarrhea,totally 110 stool samples were detected with Rotavirus,Norovirus,Sapovirus and Adenovirus,with the total detection rate 21.10%;the detection rate of Rotavirus was 7.80%,Norovirus 10.46%,Sapovirus 0.95%,Adenovirus 1.90%.There was significant difference in the detection rate of Norovirus between sexes(x2=3.869,P=0.049).Except for Adenovirus,there were significant differences in the detection rates of Rotavirus(x2=14.209,P<0.001),Norovirus(x2=13.555,P<0.001)and Spovirus(x2=6.376,P=0.024)between the years.CONCLUSION Rotavirus and Norovirus are the major pathogens detected from the viral diarrhea children aged less than 5 years old in Hohhot.The infection tends to peak in cold seasons and is prevalent among the children aged between 10 months and 20 months old,and the detection rate of viruses of the male children is higher than that of the female children.

ChildInfectious diarrheaViral diarrheaRotavirusNorovirusSapovirus

邬倩、张宇耕、云瑞涛

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内蒙古自治区妇幼保健院感染控制科,内蒙古呼和浩特 010020

内蒙古疾病预防控制中心传防所,内蒙古呼和浩特 010031

儿童 感染性腹泻 病毒性腹泻 轮状病毒 诺如病毒 札如病毒

国家科技重大专项

2017ZX10103006-003

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(10)
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