首页|床旁超声在老年脓毒症患者心功能评估中的应用及其对预后的影响

床旁超声在老年脓毒症患者心功能评估中的应用及其对预后的影响

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目的 分析重症加强护理病房(ICU)床旁超声在老年脓毒症患者心功能评估中的应用及与预后的关系.方法 选取2020年4月-2023年4月杭州市第一人民医院城北院区ICU收治的老年脓毒症患者108例,随机分为超声组和对照组,各54例;对照组采用脉搏指示剂持续心排血量法(PICCO)进行液体复苏;超声组通过床旁超声监测下进行液体复苏,记录患者性别、年龄、体质量指数(BMI)等临床资料;监测治疗前和治疗12 h后对照组和超声组心率(HR)、中心静脉压(CVP)、平均动脉压值(MAP)和中心静脉血氧饱和度(ScvO2);统计两组治疗6、12 h后液体复苏目的达标率和液体复苏用量;比较两组治疗12 h后心功能指标;记录患者机械通气时间、ICU住院时间及入院28 d时存活状况.结果 治疗12 h后,两组MAP、CVP和ScvO2升高,且超声组MAP、CVP和ScvO2高于对照组(P<0.05);两组治疗前和治疗12h后HR差异无统计学意义;治疗6、12 h后,超声组液体复苏目的达标率高于对照组,液体复苏用量小于对照组(P<0.05);超声组心脏排血量(CO)、射血分数(EF)高于对照组,二尖瓣E波速度和二尖瓣环舒张早期速度比值(E/e')低于对照组(P<0.05);两组机械通气时间、ICU住院时间、28d存活率比较差异无统计学意义.结论 ICU床旁超声指导老年脓毒症患者液体复苏治疗中,可改善患者心功能和血流动力学,提高液体复苏目的达标率,减少液体复苏用量.
Application of ICU bedside ultrasound in assessment of cardiac function in elderly patients with sepsis and impact on prognosis
OBJECTIVE To analyze the application of bedside ultrasound in intensive care unit(ICU)in the assess-ment of cardiac function of elderly patients with sepsis,and its relationship with the prognosis.METHODS A total of 108 elderly patients with sepsis admitted to ICU of Chengbei District Hangzhou First People's Hospital between Apr.2020 and Apr.2023 were selected and were divided into the ultrasound group and the control group by ran-dom number expression method,with 54 cases in each group.Fluid resuscitation was carried out in the control group by the pulse-indicator continuous cardiac output monitoring,while fluid resuscitation was carried out in the ultrasound group by bedside ultrasound monitoring,and the clinical data such as gender,age and body mass index(BMI)were recorded.Heart rate(HR),central venous pressure(CVP),mean arterial pressure(MAP)and cen-tral venous oxygen saturation(ScvO2)in the control group and the ultrasound group before and after 12 h of treat-ment were monitored.The rates of fluid resuscitation target achievement and fluid resuscitation dosage after 6 h and 12 h of treatment in both groups were statistically analyzed.The cardiac function indicators after 12h of treat-ment were compared between the two groups.The duration of mechanical ventilation,length of ICU hospitaliza-tion,and survival status at 28-day of admission were recorded.RESULTS After 12 h of treatment,MAP,CVP and ScvO2 in both groups increased,and the MAP,CVP and ScvO2 in the ultrasound group were higher than those in the control group(P<0.05).There was no statistically significant difference in HR of both groups before treatment and after 12 h of treatment.After 6 h and 12 h of treatment,the rate of fluid resuscitation target a-chievement in the ultrasound group was higher than that in the control group,while the liquid resuscitation dosage was lower than that in the control group(P<0.05).Cardiac output(CO)and Ejection fraction(EF)in the ultra-sound group were higher than those in the control group,while E/e'was lower than that in the control group(P<0.05).There was no statistically significant difference in mechanical ventilation time,length of ICU hospital-ization,and survival rate at 28-day between the two groups.CONCLUSION The application of ICU bedside ultra-sound in liquid resuscitation of elderly patients with sepsis could improve their cardiac function and hemodynamic indicators,increase the rate of fluid resuscitation target achievement,and reduce the liquid resuscitation dosage.

Intensive care unitSepsisCardiac functionPrognosis

盛莉、李海平、丁俊琳

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杭州市第一人民医院城北院区超声影像科,浙江杭州 310022

重症加强护理病房 脓毒症 心功能 预后

浙江省医药卫生科技计划杭州市生物医药和健康产业发展扶持科技专项

2020KY6902023WJC116

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(11)
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