Clinical efficacy of ear-tip blood-prick technique in treating early low-grade infected perianal abscess of fire poison accumulation
OBJECTIVE To investigate the clinical efficacy of ear-tip blood-prick technique in treating early low-grade infected perianal abscess of fire poison accumulation type.METHODS From Jan.2021 to Dec.2022,patients with early low-grade infectious perianal abscess of fire and toxicity accumulated in Lishui traditional Chinese medi-cine hospital were selected and divided into the conventional group(30 cases)and the ear-tip blood-prick group(30 cases)combined with ear-tip blood-prick technique by random number table method.Both groups were treated for 2 weeks.The clinical efficacy of the two groups after 2 weeks of treatment and the occurrence of adverse reactions during treatment were analyzed,and the levels of serum cytokines,inflammatory factors,wound blood oxygen supply,edema,and symptom and sign scores were compared between the two groups before and after 2 weeks of treatment.RESULTS After 2 weeks of treatment,the total efficacy of the ear-tip blood-prick group was signifi-cantly higher than that of the conventional group(P=0.039).After 2 weeks of treatment,the serum levels of acid fibroblast growth factor(aFGF),basic fibroblast growth factor(bFGF),transforming growth factor-β(TGF-β),wound blood flow and percutaneous partial oxygen pressure in 2 groups were increased compared with those before treatment,and those in the ear-tip blood-prick group were higher than those in the conventional group(P＜0.05).The levels of serum activin A(ACTA),hypersensitive C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),interleukin-10(IL-10)and prostaglandin E2(PGE2),wound edema,anal pain,systemic symptoms,mass size and mass texture in two groups were decreased compared with those before treatment,and those in the ear-tip blood-prick group was lower than the conventional group(P＜0.05).No serious adverse events occurred in both groups during treatment.In the ear-tip blood-prick group,2 cases of ear tip redness and swelling were self-al-leviated after the next day without treatment.In the conventional group,1 case of nausea occurred,and the symp-toms disappeared after drinking warm water.CONCLUSION Pricking blood at the tip of the ear could effectively improve the level of serum cytokines,blood oxygen supply,symptom and signs,reduce the level of inflammatory factors,and help to eliminate and heal the edema of the wound,with good curative effect and safety.
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