Association of COVID-19 infection with induced dermatoses during the epidemic
OBJECTIVE To assess skin disorders presenting during COVID-19 infection and to identify possible risk factors associated with them.METHODS Questionnaires were distributed and returned through the Easy-Expres-sion Webpage to collect information on demographics,basic medical history,and history of COVID-19.RESULTS Of 1 047 questionnaires,827 were included in the analysis.Sex,history of chronic diseases,and age were not as-sociated with skin disease during COVID-19.In multivariable analysis,patients with a history of dermatologic dis-ease were 3.998-times more likely to develop skin disease during COVID-19 infection than those without a history of dermatologic disease(OR=3.998,95％CI:2.234-7.157),those with a history of herpes were 4.434 times more likely to develop skin diseases(OR=4.434,95％CI 1.277-15.403),while subjects with a history of urti-caria were 4.907 times more likely to develop skin diseases(OR=4.907,95％CI 2.755-8.740).A history of aller-gy was also a risk factor for skin disease during COVID-19 infection,with patients with allergic being 1.807 times more likely than those without a history of allergy to develop skin disease during infection(OR=1.807,95％CI:1.049～3.113).CONCLUSION A history of allergic and dermatologic disease were risk factors for the development of skin disease during infection with COVID-19,especially a history of urticaria and herpes,and attention should be paid to the possibility of skin disease during infection with SARS-CoV-2.
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