侵袭性念珠菌病研究进展
Advances in research on invasive candidiasis
康慧 1赵静雅 2李定辰 2陈芳艳 2林杨轩 3韩黎2
作者信息
- 1. 郑州大学公共卫生学院,河南郑州 450001
- 2. 中国人民解放军疾病预防控制中心消毒与感染控制科,北京 100071
- 3. 安徽医科大学公共卫生学院,安徽合肥 230032
- 折叠
摘要
侵袭性念珠菌病(IC)是最常见的真菌感染性疾病,临床诊断困难,伴有极高的发病率和病死率,给危重症患者和免疫力低下的人群带来严重的负担.白假丝酵母是世界上大多数地区IC重点致病菌,但近年来,非白假丝酵母在一些国家和地区逐渐成为优势菌种,给临床治疗带来了极大的困难,本文综述了目前IC最新的流行病学研究进展,深入探讨IC在高危人群中的流行现状以及致病菌种的变化趋势,以期为IC的诊疗防治提供参考.
Abstract
Invasive candidiasis(IC)is the most common fungal infectious disease,which is difficult to diagnose clinically,accompanied by very high morbidity and mortality,and poses a serious disease burden to critically ill patients and immu-nocompromised individuals.Candida albicans has been the major causative agent of IC in most parts of the world,but in recent years,non-Candida albicans has gradually become the dominant species in some countries and regions,which has brought great difficulties in clinical management.This article reviews the latest epidemiologic progress of IC,and discus-ses in depth the current epidemiologic status of IC in high-risk populations as well as the trend of causative species,with the aim of providing new theoretical basis for the diagnosis and prevention of IC.
关键词
假丝酵母/侵袭性念珠菌病/高危人群/致病菌/临床表现/流行病学/预防控制Key words
Candida/Invasive candidiasis/High-risk populations/Causative agents/Clinical manifestation/Epide-miology/Prevention and control引用本文复制引用
基金项目
国家自然科学基金(82172293)
国家自然科学基金(81971914)
出版年
2024
NETL
NSTL
万方数据