Invasive candidiasis(IC)is the most common fungal infectious disease,which is difficult to diagnose clinically,accompanied by very high morbidity and mortality,and poses a serious disease burden to critically ill patients and immu-nocompromised individuals.Candida albicans has been the major causative agent of IC in most parts of the world,but in recent years,non-Candida albicans has gradually become the dominant species in some countries and regions,which has brought great difficulties in clinical management.This article reviews the latest epidemiologic progress of IC,and discus-ses in depth the current epidemiologic status of IC in high-risk populations as well as the trend of causative species,with the aim of providing new theoretical basis for the diagnosis and prevention of IC.
CandidaInvasive candidiasisHigh-risk populationsCausative agentsClinical manifestationEpide-miologyPrevention and control
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