Risk factors of coronary artery lesions in children with Kawasaki disease
OBJECTIVE To analyze the effect of risk factors of pediatric Kawasaki disease complicated with coronary artery lesions.METHODS A total of 80 children with Kawasaki disease admitted to Yichun People's Hospital from Oct 2021 to Jun 2023 were divided into the coronary artery disease group(28 cases)and the non-coronary artery disease group(52 cases)according to whether the concomitant coronary artery lesions occurred.The general de-mographic characteristics(age,gender,clinical symptoms,etc.)and potential risk factors(such as gender,infec-tion factors,etc.)for coronary artery disease were investigated by retrospective analysis.Statistical software was used for statistical analysis,and logistic regression analysis was used to analyze the ralated risk factors of coronary artery disease.RESULTS Univariate analysis showed that there were significant differences in gender,fever time,mycoplasma pneumoniae,EB virus,cytomegalovirus,streptococcus pneumoniae and gamma globulin between the two groups(P＜0.05).According to the results of logistic multiple regression analysis,the independent risk fac-tors for coronary artery comorbidities included male gender,fever duration ≥7,etc.(P＜0.05).CONCLUSION The risk factors that lead to coronary artery complications in children with Kawasaki disease are relatively com-plex.It is necessary to strengthen the focus of care for such children,take effective measures to intervene,pro-mote the recovery of their condition,and provide support for the improvement of their prognosis.
NETL
NSTL
万方数据
