Epidemiologic investigation of catheter-associated bloodstream infections in NICU
OBJECTIVE To investigate the epidemiology of catheter-related bloodstream infections(CRBSI)in a neonatal intensive care unit(NICU),and in order to provide a scientific basis for infection prevention and control.METHODS The three-room distribution of infected children from May 28 to Jun 24,2023 was investigated.Envi-ronmental hygiene samples were collected from the NICU.The nasal passages and hands samples of medical staff were actively screened to find Staphylococcus aureus(SA).And pulsed-field gel electrophoresis(PFGE)was per-formed to analyze the homology with the strains detected by blood culture of the children.RESULTS The rate of CRBSI infection in children in NICU was 2.29‰,nasal SA-positive rate among medical staff was 32.35％,and hand SA-positive rate was 1.47％.PFGE test analysis showed that strains isolated from blood culture of two chil-dren's specimens had 91.30％similarity to one strain from a nurse's nasal specimen,and one strain from child's blood culture was 91.30％similar to a strain from another nurse's hand.CONCLUSION Three children with CRBSI were related to nasal colonization of SA and hand hygiene of medical staff,which are the two pathways of infec-tion,excluding outbreak of nosocomial infection.Great attention should be paid to the nasal SA colonization of NICU medical staff,and timely de-colonization management,strict implementation of hand hygiene should be car-ried out,in order to actively reduce the incidence of hospital infections.
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