Carbapenem antibiotics are known as the last line of defense against pathogenic bacteria,however,the Acinetobacter baumannii shows an increasingly drug resistance in recent years and has become one of most chal-lenging hospital-acquired pathogens worldwide.As natural killers against bacteria,phages have great potential in tackling the growing threat of multidrug resistance.In this review,most of the current studies on bacteriophage a-gainst A.baumannii were summarized in terms of single phage therapy,bacteriophage cocktail therapy,bacterio-phage derived enzymes against pathogens,and the therapeutic effects were discussed.This paper aims to provide a more comprehensive understanding of A.baumannii phages and theoretical support for the clinical application of A.baumannii phages.