Impact of bundles of care on incidence of nosocomial infection in a general ICU
OBJECTIVE To evaluate the impact of bundles of care on the incidence of nosocomial infection in a gen-eral Intensive care unit(ICU).METHODS By means of a quasi-experimental design with a pre-and post-comparison approach,the patients who were hospitalized in general ICU from Aug 2021 to Jul 2022 were assigned as the con-trol group according to inclusion and exclusion criteria,and the patients who were hospitalized in general ICU from Aug 2022 to Jul 2023 were assigned as the intervention group.The bundles of prevention and control intervention measures for infections were taken in the intervention group on basis of the conventional management.The inci-dence of nosocomial infection was statistically analyzed before and after the intervention.RESULTS There were 1089 patients in the control group and 895 patients in the intervention group.The Acute Physiology and Chronic Health E-valuation(APACHE)Ⅱ score of the control group was[20(14,24)],similar to[20(14,25)]of the intervention group(Z=-0.907,P=0.365).The incidence of nosocomial infection of the intervention group was 2.35%,lower than 4.50%of the control group(x2=6.691,P=0.010).The incidence of lower respiratory tract infection of the interven-tion group was 0.67%,lower than 1.93%of the control group(x2=5.791,P=0.016);the incidence of bloodstream infection of the intervention group was 0.11%,lower than 1.38%of the control group(x2=9.838,P=0.002);the in-cidence of urinary catheterrelated urinary tract infection of the intervention group was 0.800 case/1 000 catheter day,lower than 2.448 case/1 000 catheter day of the control group(U=2.202,P=0.028).There were no significant differ-ences in the incidence rates of nosocomial infections of other sites.CONCLUSION The bundles of care can effectively re-duce the incidence of nosocomial infection in the general ICU,especially the incidence of lower respiratory tract infection,bloodstream infection and urinary catheter-related urinary tract infection.
BundleIntervention measureIntensive care unitNosocomial infection