中华医院感染学杂志2024,Vol.34Issue(18) :2865-2869.DOI:10.11816/cn.ni.2024-248025

耐碳青霉烯类肠杆菌研究进展

Progression of research on carbapenem-resistant Enterobacteriaceae

江海宁 张启飞 方向兰 胡朕瑜 孟昆 谢多双
中华医院感染学杂志2024,Vol.34Issue(18) :2865-2869.DOI:10.11816/cn.ni.2024-248025

耐碳青霉烯类肠杆菌研究进展

Progression of research on carbapenem-resistant Enterobacteriaceae

江海宁 1张启飞 1方向兰 1胡朕瑜 1孟昆 2谢多双3
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作者信息

  • 1. 湖北医药学院公共卫生与健康学院,湖北十堰 442099
  • 2. 湖北医药学院附属太和医院感染与免疫性疾病研究所,湖北十堰 442099
  • 3. 湖北医药学院附属太和医院防保感控处,湖北十堰 442099
  • 折叠

摘要

耐碳青霉烯类肠杆菌(CRE)感染已成为全球范围内公共卫生关注的焦点之一.CRE对多种碳青霉烯类抗菌药物表现出高度耐药性,其治疗选择受到极大限制,从而增加了医疗成本并提高了患者病死率.尽管目前对于CRE的研究已经取得了一定的进展,但鉴于其耐药性的复杂性和持续变化,要有效控制CRE感染仍需全球公共卫生机构、医疗机构及科研机构的共同努力.本研究旨在系统总结近年来有关CRE耐药机制、流行病学现状以及防控策略的研究进展,以期在此基础上制定更有效的预防和控制策略,为进一步减少CRE感染的发生和传播并保障公众健康提供参考.

Abstract

Carbapenem-resistant Enterobacteriaceae(CRE)is a type of multidrug-resistant organism,and the CRE infection has become a public health concern worldwide.CRE exhibits high degree of resistance to a wide range of carbapenem antibiotics,and the choice of drug therapies is limited at great extent,which therefore increases the medical cost and raises the mortality rate.Although the research on CRE has made certain achievement,the global public health institution,medical institutions and scientific research institutions should make the joint efforts to ef-fectively control the CRE infection due to the complexity and continuous change of drug resistance.The research aims to systematically summarize the progress of research on the drug resistance mechanisms,current status of epidemiology and prevention strategies so as to put forward more effective prevention and control strategies,fur-ther reduce the incidence of CRE infection and provide guidance for ensuring the public health.

关键词

耐碳青霉烯类肠杆菌/耐药机制/流行分布/防控策略

Key words

Carbapenem-resistant Enterobacteriaceae/Drug resistance mechanism/Epidemiological distribution/Prevention and control strategy

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基金项目

国家自然科学基金青年项目(32200156)

出版年

2024
中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCDCSCD北大核心
影响因子:1.885
ISSN:1005-4529
参考文献量18
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