Progression of research on carbapenem-resistant Enterobacteriaceae
Carbapenem-resistant Enterobacteriaceae(CRE)is a type of multidrug-resistant organism,and the CRE infection has become a public health concern worldwide.CRE exhibits high degree of resistance to a wide range of carbapenem antibiotics,and the choice of drug therapies is limited at great extent,which therefore increases the medical cost and raises the mortality rate.Although the research on CRE has made certain achievement,the global public health institution,medical institutions and scientific research institutions should make the joint efforts to ef-fectively control the CRE infection due to the complexity and continuous change of drug resistance.The research aims to systematically summarize the progress of research on the drug resistance mechanisms,current status of epidemiology and prevention strategies so as to put forward more effective prevention and control strategies,fur-ther reduce the incidence of CRE infection and provide guidance for ensuring the public health.
Carbapenem-resistant EnterobacteriaceaeDrug resistance mechanismEpidemiological distributionPrevention and control strategy
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