首页|2019-2022年某院骨科创伤患者创面厌氧菌感染病原菌及其耐药性

2019-2022年某院骨科创伤患者创面厌氧菌感染病原菌及其耐药性

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目的 探究2019-2022年某院骨科创伤患者创面厌氧菌感染病原菌及耐药性.方法 选取2019-2022年十堰市人民医院骨科收治的233例创面厌氧菌感染患者作为研究对象,获取患者临床资料,分析其临床特征、病原学结果及药敏结果.结果 233例患者中以男性(77.68%)、年龄以≥60岁(43.78%)、术中采集组织(48.50%)、Ⅲ型伤口(75.54%)、混合细菌感染(74.68%)、治愈(91.42%)为主要特征,且患者感染指标均较正常水平升高;233例患者共检出307株厌氧菌,革兰阳性厌氧菌为主占58.31%,其中梭菌属占24.42%,厌氧消化链球菌占14.98%,大芬戈尔德菌占9.12%;革兰阴性厌氧菌占41.69%,其中普雷沃菌属占15.64%,拟杆菌属占11.72%,梭菌属占7.17%;需氧菌分离出181株,其中革兰阳性需氧菌占62.43%,革兰阴性需氧菌占37.57%;革兰阳性厌氧菌和革兰阴性厌氧菌在手部伤占比较高(P<0.05);梭菌属对甲硝唑、克林霉素和青霉素的耐药率<30%,消化链球菌、普雷沃氏菌、拟杆菌对甲硝唑、克林霉素和青霉素耐药率<48%.结论 厌氧菌是骨科创伤患者创面感染的主要致病菌,临床应加强骨科创伤患者创面厌氧菌培养,巩固治疗效果.
Analysis of pathogenic bacteria of anaerobic bacterial infections in trauma wounds of orthopedic trauma patients and drug resistance in a hospital,2019 to 2022
OBJECTIVE To explore the pathogenic bacteria of anaerobic bacterial infections in trauma wounds of or-thopedic trauma patients in a hospital from 2019 to 2022.METHOD A total of 233 patients with wound anaerobic bacteria infections admitted to the Department of Orthopedics of a hospital from 2019 to 2022 were selected as the study subjects,the clinical data of the patients were obtained,and their clinical characteristics,etiological results and drug susceptibility results were analyzed.RESULTS The 233 patients were mainly characterized by males(77.68% ),age of ≥60 years(43.78% ),intraoperative collection of tissue(48.50% ),type Ⅲ wounds(75.54% ),mixed bacterial infections(74.68% ),and healing(91.42% ),and the infection indicators of patients were elevated compared to the normal level.A total of 307 strains of anaerobic bacteria were detected in 233 cases,with gram-positive anaerobic bacteria predominating in 58.31% of the cases,of which Clostridium accounted for 24.42% ,anaerobic digestion Streptococcus accounted for 14.98% ,and Fingoldia dahliae accounted for 9.12% .Gram negative anaerobic bacteria accounted for 41.69% ,of which Prevotella accounted for 15.64% ,Bacteroides accounted for 11.72% ,Fusobacterium accounted for 7.17% .181 strains of aerobic bacteria were isolated,of which gram-positive aerobic bacteria accounted for 62.43% and gram-negative aerobic bacteria accounted for 37.57% .Gram-positive anaerobes and gram-negative anaerobes accounted for a relatively high proportion of hand injuries(P<0.05).The resistance rate of Clostridium to metronidazole,clindamycin and penicillin was less than 30% ,and the resistance rate of Peptostreptococcus,Prevotella and Bacteroides to metronidazole,clindamycin and peni-cillin was less than 48% .CONCLUSION Anaerobic bacteria were the main pathogenic bacteria of wound infection in orthopedic trauma patients in a hospital,and the culture of anaerobic bacteria on the wounds of orthopedic trau-ma patients should be strengthened in the clinic to consolidate the treatment effect.

OrthopedicsTraumaWoundsPathogenInfectionEtiologyDrug resistance

闵晓燕、纪涛涛

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十堰市人民医院(湖北医药学院附属人民医院)骨科中心,湖北十堰 442000

骨科 创伤 创面 厌氧菌 感染 病原菌 耐药性

湖北省教育厅科研计划基金资助项目

Q20182101

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(19)