Risk factors for catheter-related infections in patients with deep venous cannulae and construction of their prediction model
OBJECTIVE To explore the risk factors for catheter-related infections(CRI)in patients with deep vein catheterization and construct their prediction model.METHODS The clinical data of 109 patients who underwent deep vein catheterization in the Affiliated Hospital of Ningbo University School of Medicine from Sep.2019 to Sep.2022 were selected for retrospective analysis,and the patients were divided into the combined CRI group(27 ca-ses)and the no CRI group(82 cases)according to their CRI status.The pathogenic bacteria in the combined CRI group were statistically analyzed,the risk factors for the occurrence of CRI in the patients with deep vein catheter-ization were summarized,and the receiver operating characteristic(ROC)curves were plotted to analyze the pre-dictive value of the prediction model for the occurrence of CRI in patients with deep vein catheterization,obtaining their area under the curve(AUC),sensitivity,and specificity.RESULTS A total of 37 strains of pathogens were detected in 27 patients with deep vein catheterization who developed CRI,of which 19 strains of gram-negative bacteria accounted for 51.35％ ,14 strains of gram-positive bacteria accounted for 37.84％ ,and 4 strains of fungi accounted for 10.81％ .Comorbid diabetes mellitus and serum albumin(ALB)were risk factors for CRI in patients with deep vein catheterization(OR=5.043,3.873,P＜0.05).The regression model was constructed as follows:logit(P)=-10.114+diabetes × 1.618+ALB × 1.354.The ROC curve for the occurrence of CRI in patients with deep vein catheterization were plotted according to the predictive probability logit(P),with an AUC value of 0.886,a sensitivity of 92.59％ ,and a specificity of 69.51％ when logit(P)＞11.00.CONCLUSIONS The risk fac-tors of CRI in patients with deep vein catheterization included comorbid diabetes mellitus and serum ALB,accord-ing to which the construction of regression model had a good predictive value for the occurrence of CRI in patients with deep vein catheterization,and the main pathogens of infection were gram-negative bacteria.Clinically,targe-ted intervention or prevention could be carried out for high-risk groups to reduce the risk of the occurrence of CRI.
Deep venous indwelling catheterCatheter associated infectionPathogenRisk factorPrediction model
NETL
NSTL
万方数据
