首页|431例奥密克戎变异株新冠感染者临床表现及其危险因素

431例奥密克戎变异株新冠感染者临床表现及其危险因素

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目的 分析某医院收治的(含隔离)新型冠状病毒感染者症状及其危险因素。方法 2022年12月22日-2023年1月10日收集就诊于解放军第三○五医院的确诊为新型冠状病毒感染患者的人口统计学基本信息、主要临床症状、流行病学史、疫苗接种史、吸烟饮酒史和感染期间药物服用情况等信息,并对数据进行统计描述及分析。结果 共收集病例数据431例,男性331例(76。80%),年龄以21~30岁为主,6。03%感染者有基础疾病;379例(87。94%)出现感染相关症状,症状主要表现为发热、咳嗽咳痰、咽干咽痛、鼻塞流涕、身体疼痛等,出现症状持续时长集中在2。00~4。00天,服用药物主要是连花清瘟、布洛芬等;女性、不吸烟者出现症状的阳性率和症状程度高于男性和吸烟者,二元Logistic回归模型显示男性、吸烟可能是该模型的保护因素。结论 431例感染者新冠症状主要表现为发热、咳嗽咳痰、咽干咽痛、鼻塞流涕和身体疼痛等,以轻症为主,人群体质好且年轻化,其产生的保护作用可能大于性别和吸烟带来的影响。
Clinical performance 431 patients with SARS-CoV-2 infection with Omicron variant and their risk factor analysis
OBJECTIVE To analyze the symptoms and influencing factors of patients with SARS-CoV-2 in a hospi-tal.METHODS From Dec.22,2022 to Jan.10,2023,the basic demographic information,main clinical symp-toms,epidemiological history,vaccination history,smoking and drinking history,and drug use during infection of patients with confirmed SARS-CoV-2 infection in the 305 Hospital of PLA were collected,and the data were sta-tistically described and analyzed.RESULTS A total of 431 cases were collected,including 331 males(76.80%),aged 21-30 years,and 6%of the infected people had underlying diseases.379 people(87.94%)had infection re-lated symptoms,mainly including fever,cough and expectoration,dry throat and sore throat,nasal congestion and runny nose,body pain,etc.The duration of symptoms was concentrated in 2.00-4.00 days,and the drugs were mainly Lianhua Qingwen,ibuprofen,etc.The positive rate and severity of symptoms of female and non-smokers were higher than those of male and smokers.The binary logistic regression model showed that male and smoking might be the protective factors of the model.CONCLUSIONS The symptoms of the SARS-CoV-2 in 431 patients were mainly fever,cough and expectoration,dry and sore throat,nasal congestion and runny nose,physi-cal pain,etc.,which were predominately mild diseases.The population were in good health and young,which might produce a protective effect greater than that brought about by gender and smoking.

SARS-CoV-2 infectionSymptomRisk factor

罗心越、孙风清、郭运达、刘梦颖、顾培耕、王立贵、祝丙华

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南方医科大学公共卫生学院,广东 广州 510515

中国人民解放军第三○五医院疾控科,北京 100017

61889部队卫生科,北京 100017

61889部队门诊部,北京 100017

中国人民解放军第三○五医院耳鼻喉科,北京 100017

中国人民解放军疾病预防控制中心,北京 100080

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新型冠状病毒感染 症状 危险因素

国家重点研发计划基金资助项目&&

plan2022YFC2602304145AHQ080020005X

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(20)