首页|综合医院老年住院患者多药耐药菌感染的流行病学特征

综合医院老年住院患者多药耐药菌感染的流行病学特征

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目的 回顾分析某综合医院2019-2023年(不包括2020年)老年住院患者的多药耐药菌感染流行病学特征。方法 收集2019-2023年(不包括2020年)解放军总医院第三医学中心检出的所有多药耐药菌感染资料。分析2019-2023年(不包括2020年)多药耐药菌分布及耐药情况以及老年患者感染部位等资料。结果 2019-2023年(不包括2020年),住院患者中65岁及以上人群医院感染多药耐药菌338例,检出次数总计为2 042次,检出多药耐药菌2 777株。多药耐药菌感染患者气管插管、使用呼吸机和泌尿道插管占比较高;主要的感染部位为呼吸系统。检出的多药耐药菌以碳青霉烯类耐药鲍氏不动杆菌和耐三四代头孢肺炎克雷伯菌为主。2019-2023年(不包括2020年)耐甲氧西林金黄色葡萄球菌检出率呈下降趋势(P=0。037)。结论 老年患者多药耐药菌耐药谱有一定变化;且以呼吸系统和呼吸道为主要感染部位,建议对气管插管、使用呼吸机和泌尿道插管老年患者予以关注,预防多药耐药菌感染。
Epidemiologic characteristics of multidrug-resistant bacterial infections in elderly hospitalized patients in general hospital
OBJECTIVE To retrospectively analyze the epidemiologic characteristics of multidrug-resistant bacterial infections among elderly inpatients at a general hospital from 2019 to 2023(excluding 2020).METHODS Data on all multidrug-resistant bacterial infections detected at the Third Medical Center of the People's Liberation Army General Hospital from 2019 to 2023(excluding 2020)were collected.The information on the distribution and re-sistance of multidrug-resistant bacteria from 2019 to 2023(excluding 2020),as well as data on infection sites in elderly patients were analyzed.RESULTS From 2019 to 2023(excluding 2020),there were 338 cases of hospital-acquired multidrug-resistant bacteria among hospitalized patients aged 65 and older,with a total of 2,042 detec-tions and 2,777 strains of multidrug-resistant bacteria detected.Patients with multidrug-resistant bacterial infec-tions had a high proportion of Endotracheal,use of ventilators,and urinary tract intubation;The predominant site of infection was the respiratory system.The detected multidrug-resistant bacteria were predominantly carbapenem resistant Acinetobacter baumannii and third-generation cephalosporin resistant Klebsiella pneumoniae.The detec-tion rate of methicillin-resistant Staphylococcus aureus showed a decreasing trend from 2019 to 2023(excluding 2020)(P=0.037).CONCLUSIONS There were certain changes in the resistance spectrum of multidrug-resistant bacteria in elderly patients.The respiratory system and respiratory tract were the main sites of infection,it is rec-ommended that attention should be paid to prevent multidrug-resistant bacterial infections in elderly patients with endotracheal intubation,use of ventilators,and urinary tract intubation.

Hospital acquired infectionsMultidrug resistant bacteriaAntibacterial drugDrug resistance rateInfection siteEpidemiologyRisk factor

杨慧宁、杨海宁、黄姝瑜、张娜、郭东临、张振宇

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解放军总医院第三医学中心疾病预防控制科,北京 100039

武警青海总队医院急诊科,青海西宁 810000

北京大学公共卫生学院,北京 100191

医院感染 多药耐药菌 抗菌药物 耐药率 感染部位 流行病学 危险因素

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(23)