Epidemiologic characteristics of multidrug-resistant bacterial infections in elderly hospitalized patients in general hospital
OBJECTIVE To retrospectively analyze the epidemiologic characteristics of multidrug-resistant bacterial infections among elderly inpatients at a general hospital from 2019 to 2023(excluding 2020).METHODS Data on all multidrug-resistant bacterial infections detected at the Third Medical Center of the People's Liberation Army General Hospital from 2019 to 2023(excluding 2020)were collected.The information on the distribution and re-sistance of multidrug-resistant bacteria from 2019 to 2023(excluding 2020),as well as data on infection sites in elderly patients were analyzed.RESULTS From 2019 to 2023(excluding 2020),there were 338 cases of hospital-acquired multidrug-resistant bacteria among hospitalized patients aged 65 and older,with a total of 2,042 detec-tions and 2,777 strains of multidrug-resistant bacteria detected.Patients with multidrug-resistant bacterial infec-tions had a high proportion of Endotracheal,use of ventilators,and urinary tract intubation;The predominant site of infection was the respiratory system.The detected multidrug-resistant bacteria were predominantly carbapenem resistant Acinetobacter baumannii and third-generation cephalosporin resistant Klebsiella pneumoniae.The detec-tion rate of methicillin-resistant Staphylococcus aureus showed a decreasing trend from 2019 to 2023(excluding 2020)(P=0.037).CONCLUSIONS There were certain changes in the resistance spectrum of multidrug-resistant bacteria in elderly patients.The respiratory system and respiratory tract were the main sites of infection,it is rec-ommended that attention should be paid to prevent multidrug-resistant bacterial infections in elderly patients with endotracheal intubation,use of ventilators,and urinary tract intubation.