Clinical manifestations and epidemiological characteristics of children with Mycoplasma pneumoniae infection in 3 hospitals of Liaoning Province
OBJECTIVE To investigate the prevalence of Mycoplasma pneumoniae infection in children hospitalized in pediatric internal medicine in some parts of Liaoning Province of China,and to analyze the clinical characterics and bronchoscopic manifestations of children with severe M.pneumoniae pneumonia(SMPP).METHODS From Jan.1,2017 to Dec.31,2023,a total of 340,681 hospitalized children from three tertiary hospitals in Liaoning Province were enrolled in this study and the positive rate of M.pneumoniae infection were analyzed every month.In addition,the age distribution and respiratory disease spectrum changes of M.pneumoniae infection in children,and clinical and microscopic manifestations of children with SMPP were also explored.RESULTS The proportion of M.pneumoniae infection in hospitalized children was 27.25％;it occurred highly in autumn and winter and showed a sharp increase since Aug.2023.The majority of hospitalized children with M.pneumoniae infection are children aged 1 to 4 years(46.34％)and 4 to 7 years(22.97％).Bronchopneumonia was the main manifestation of respiratory tract disease caused by M.pneumoniae infection(55.74％);meanwhile,it account for 23.12％in SMPP.It was manifested by bronchoscope that most of the mucosa presented congestion(63.91％)and plica(28.84％),and the sputums presented mainly flocculent(51.26％)and mucus casts(24.63％).It was notewor-thy that in 2023 the proportion of plastic sputum casts rised significantly(8.61％).CONCLUSION:In some parts of Liaoning Province of China,M.pneumoniae is the main pathogen for the infection of hospitalized children.M.pneu-moniae infection is most common in hospitalized children aged 1 to 7 years with a high occurance in autumn and winter.After the COVID-19,it shows a delayed outbreak trend,and the number of severe cases and complications increases sig-nificantly.It is worthy of attention.
Mycoplasma pneumoniaeSevere M.pneumoniae pneumoniaBronchoscopic manifestationAge dis-tributionDisease spectrumLiaoning Province
万方数据
维普
