首页|短时消毒法对基层医院共享母乳病原菌与营养成分和免疫活性物质的影响

短时消毒法对基层医院共享母乳病原菌与营养成分和免疫活性物质的影响

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目的 旨在探讨短时消毒法对基层医院共享母乳病原菌、营养成分和免疫活性物质的影响.方法 选取2022年11月-2023年10月即将存放于浙江省龙游县人民医院共享母乳库的110份母乳为研究对象.对短时消毒前后母乳的细菌检出情况、标准菌株杀灭情况、营养成分及免疫活性物质等进行比较.结果 在短时消毒前,110份母乳标本中,检出细菌26份(23.64%),在短时消毒后,110份母乳标本中,检出细菌3份(2.73%),短时消毒后母乳的细菌检出率低于短时消毒前(P<0.05);短时消毒法对无菌母乳内标准菌株的杀灭率>99.99%;在短时消毒前后,碳水化合物、脂肪、蛋白质及干物质等营养成分数差异无统计学意义;短时消毒前后,免疫球蛋白G(IgG)、IgM、分泌型免疫球蛋白A(sIgA)、溶菌酶及乳铁蛋白等免疫活性物质数值均差异无统计学意义.结论 短时消毒法用于基层医院共享母乳库的母乳消毒,可显著降低母乳的细菌检出率,细菌杀灭率高,对母乳中的营养成分和免疫活性物质影响较小.
Effects of short-time disinfection on pathogenic bacteria,nutrients and immunoactive substances in shared breast milk in primary hospitals
OBJECTIVE To explore the effects of short-time disinfection on pathogenic bacteria,nutrients and im-munoactive substances in shared breast milk in primary hospitals.METHODS A total of 110 samples of breast milk that would be stored in the shared breast milk bank of Longyou County People's Hospitals in Zhejiang Prov-ince from Nov.2022 to Oct.2023 were selected as the study subjects.Bacterial detection,killing of standard strains,nutritional composition and immunoactive substances of breast milk before and after short-term disinfec-tion were compared.RESULTS Before short-term disinfection,bacteria were detected in 26(23.64%)out of 110 breast milk samples,and after short-term disinfection,bacteria were detected in 3(2.73%)out of 110 breast milk samples.The bacterial detection rate of breast milk after short-term disinfection was significantly lower than that before short-term disinfection(P<0.05).The killing rate of standard strains of bacteria in sterile breast milk was more than 99.99%.There were no significant differences in the nutrient ratios of carbohydrate,fat,proteins and dry matter before and after short-term disinfection.There were no significant differences in the values of immuno-active substances such as IgG,IgM,sIg A,lysozyme and lactoferrin before and after short-term disinfection.CONCLUSION The short-term disinfection method used for breast milk disinfection in shared breast milk ware-houses of grassroots hospitals can significantly reduce the bacterial detection rate of breast milk,with a high bac-terial killing rate and minimal impact on the nutritional components and immunologically active substances in breast milk.

Short-time disinfection methodShared breast milk banksBreast milkDisinfectEffectPathogenNutrientImmunoactive substance

汪红姣、郁银娟、徐娟妹、钱珺、俞君

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浙江省龙游县人民医院新生儿科,浙江龙游 324400

浙江大学附属儿童医院新生儿科,浙江 杭州 310005

短时消毒法 共享母乳库 母乳 消毒 效果 病原菌 营养成分 免疫活性物质

2024

中华医院感染学杂志
中华预防医学会 中国人民解放军总医院

中华医院感染学杂志

CSTPCD北大核心
影响因子:1.885
ISSN:1005-4529
年,卷(期):2024.34(23)