With the development of medical technology,the relationship between pulmonary microbiome and venti-lator-associated pneumonia(VAP)draws increasing attention.As a type of common hospital-acquired infection among mechanical ventilation patients,VAP is closely associated with the imbalance of pulmonary microbiome.However,the cognition of changes of pulmonary microbiome and action mechanisms and relevant studies remains insufficient during the process of emergence and development of VAP.The progress of research on the pulmonary microbiome that the scholars of China and abroad engaged in is reviewed in the article,the interaction between the pulmonary microbiome and the emergence and development of VAP is explored,and the value of change of pulmo-nary microbiome in early diagnosis of VAP is emphasized.The prevention strategies for regulation of pulmonary microbiome are proposed so as to offer new perspective for prevention of VAP,management and treatment of the patients.
关键词
肺部微生物组/呼吸机相关肺炎/气管插管/控制策略/微生物菌群失调
Key words
Pulmonary microbiome/Ventilator-associated pneumonia/Endotracheal intubation/Control strategy/Imbalance of microbial flora