44例胸部受累的淋巴瘤临床分析
Clinical Analysis of 44 Cases of Lymphoma Involving the Chest
郑蓉珊 1张宏英1
作者信息
- 1. 350008 福建福州,福建省福州肺科医院呼吸与危重症医学科
- 折叠
摘要
目的 分析胸部受累淋巴瘤的临床特征、诊断方法、病理类型,以提高临床认知和诊断率.方法 回顾性收集并整理2017年7月至2022年8月就诊于福建省福州肺科医院,经病理诊断为淋巴瘤的44例患者的临床资料及病理诊断等,根据病灶受累部位分为胸部病灶组及全身病灶组进行分析.结果 44例患者中胸部病灶组23例,全身病灶组21例,全身病灶组纵隔淋巴结肿大18(85.7％)例,较胸部病灶组11(47.8％)例多,差异具有统计学意义(P＜0.05).胸部病灶组多以CT引导下肺穿刺活检(11例)、支气管镜下活检(6例)明确诊断,而全身病灶组多以浅表淋巴结活检(13例)获取病理诊断.胸部病灶组以成熟B细胞肿瘤中边缘区淋巴瘤为主,还包括前体淋巴细胞肿瘤;全身病灶组病理类型仅有成熟B细胞肿瘤和成熟T细胞和NK细胞肿瘤.结论 因为淋巴瘤症状不典型,针对浅表淋巴结肿大患者,淋巴结活检诊断价值较高,针对肺部病灶为主的患者,在CT引导下肺穿刺活检有一定的诊断价值,必要时可多学科讨论.
Abstract
Objective To analyze the clinical characteristics,diagnostic methods,and pathological types of lymphoma with thoracic involvement,with the aim of enhancing clinical awareness and diagnostic rates.Methods A retrospective collection of 44 patients diagnosed with lymphoma through pathological examination at the Fujian Provincial Fuzhou Pulmonary Hospital from July 2017 to August 2022 was conducted.Clinical data and pathological diagnoses were collected,and the patients were divided into two groups for analysis based on the location of the lesion:the thoracic lesion group and the systemic lesion group.Results Among the 44 patients,23 patients were in the thoracic lesion group,and 21 patients were in the systemic lesion group.Mediastinal lymph node enlargement was observed in 18(85.7％)patients in the systemic lesion group,significantly more than 11(47.8％)patients in the thoracic lesion group(P＜0.05).Diagnoses in the thoracic lesion group were mainly confirmed by CT-guided lung biopsy(11 cases)and bronchoscopic biopsy(6 cases),while in the systemic lesion group,superficial lymph node biopsy(13 cases)was predominantly used for obtaining a pathological diagnosis.The thoracic lesion group primarily consisted of mature B-cell tumors,including marginal zone lymphoma and precursor lymphocytic tumors,while the systemic lesion group had only mature B-cell tumors and mature T-cell and NK-cell tumors.Conclusion Since Lymphoma symptoms are atypical,Lymph node biopsy is highly valuable for diagnosing patients with superficial lymph node enlargement,while CT-guided lung biopsy has a certain diagnostic value for patients with pulmonary lesions,and multidisciplinary discussions may be necessary when needed.
关键词
淋巴瘤/胸部/影像/病理学Key words
lymphoma/thorax/imaging/pathology引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据