摘要
目的 分析急诊室上性心动过速治疗中酒石酸美托洛尔和胺碘酮静脉给药的疗效、不良反应及复律效果.方法 回顾性选取2020年2月至2023年2月邹平市人民医院急诊室上性心动过速患者100例,依据用药方法分为酒石酸美托洛尔和胺碘酮静脉给药组(联合用药组)、单独胺碘酮静脉给药组(单独用药组),每组各50例.比较两组患者动脉血压(平均动脉压、舒张压、收缩压)、血液流变学指标、不良反应发生情况、药物起效时间、复律时间以及疗效评定.结果 联合用药组患者的平均动脉压、舒张压、收缩压、血细胞比容、红细胞沉降率、纤维蛋白原水平、不良反应发生率均低于单独用药组,总有效率高于单独用药组,药物起效时间、复律时间均短于单独用药组(P值均<0.05).结论 急诊室上性心动过速治疗中酒石酸美托洛尔和胺碘酮静脉给药的疗效较单独胺碘酮静脉给药显著,且不良反应更少,复律时间更短.
Abstract
Objective To analyze the efficacy,side effects,and cardioversion effects of intravenous administration of Metoprolol Tartrate and Amiodarone in the treatment of supraventricular tachycardia in the emergency room.Methods 100 patients with supraventricular tachycardia in the emergency room of Zouping People's Hospital from February 2020 to February 2023 were retrospectively selected.According to the medication method,they were divided into two groups:the combination group of Metoprolol Tartrate and Amiodarone intravenous administration(combination group)and the group of Amiodarone intravenous administration alone(single group),with 50 cases in each group.We compared arterial blood pressure(mean arterial pressure,diastolic pressure,systolic pressure),hemorheological indicators,the occurrence of adverse reactions,drug onset time,recovery time,and efficacy evaluation between two groups of patients.Results The average arterial pressure,diastolic blood pressure,systolic blood pressure,hematocrit,erythrocyte sedimentation rate,and fibrinogen content of the combination therapy group were lower than those of the single group.Compared to the single group,in the combination group,the total effective rate was higher,the incidence of side effects was lower,the onset time of the drug was shorter,and the recovery time was shorter(P<0.05).Conclusion In the treatment of supraventricular tachycardia in the emergency room,intravenous administration of Metoprolol Tartrate and Amiodarone is more effective than intravenous administration of amiodarone alone,with less side effects and shorter cardioversion time.