Objective To observe and analyze the effect of minimally invasive trans-thoracic ventricular septal defect closure.Methods 100 patients who received minimally invasive transthoracic ventricular septal de-fect closure in the Affiliated Hospital of Guizhou Medical University from February 2018 to December 2023 were retrospectively selected,all with single defects.Their clinical data were collected,and the effect of closure was analyzed.Results 97 out of 100 patients were successfully closed,with a success rate of 97％(P＜0.001).Three patients were switched to hypothermic cardiopulmonary bypass surgery.Among the 97 successfully closed patients,41 cases were treated witheccentric occluders,and 56 cases were treated with equilateral occluders.More patients were treated with equilateral occluders(P＜0.05).After 3 to 6 months of follow-up,one patient experienced residual shunt,and the shunt disappeared after the occluder model was replaced and closedagain.Conclusion Minimally invasive transthoracicventricular septal defectclosure has a high success rate and a relatively low incidence of com-plications,which can be widely used in clinic.
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