Objective To explore the clinical feasibility of treating bacterial conjunctivitis with gatifloxacin ophthalmic gel.Methods 118 patients with bacterial conjunctivitis who treated in our hospital from November 2022 to November 2023 were randomly divided into the observation group(gatifloxacin ophthalmic gel,n=59)and the control group(levofloxacin ophthalmic gel,n=59).Clinical response rate and bacterial clearance rate in both groups of patients and the occurrence of adverse reactions during treatment were observed.Results After 14 days of treatment,the clinical symptoms and signs of the two groups were reduced,and the amount of reductionin the observation group was more obvious than that in the control group(94.92%vs 81.36%,X2=5.187,P=0.023).The bacterial infection rate in both groups was reduced,and the bacterial clearance rate in the observation group was more obvious than that in the control group(91.53%vs 74.57%,x2=6.020,P=0.014).The incidence of adverse reactions in the observation group was 1.69%,which was not significantly different from that in the control group(3.39%)(P=0.559).Conclusion Treating bacterial conjunctivitis with gatifloxacin ophthalmic gel has good effi-cacy,strong antibacterial activity,and high safety.