中华灾害救援医学2024,Vol.11Issue(5) :612-614.DOI:10.13919/j.issn.2095-6274.ZHJY202404006

地氯雷他定干混悬剂联合布地奈德对小儿慢性咳嗽的临床效果观察

Observation on the Clinical Effect of Desloratadine Dry Suspension Combined with Budesonide on Chronic Cough in Children

戴春宝
中华灾害救援医学2024,Vol.11Issue(5) :612-614.DOI:10.13919/j.issn.2095-6274.ZHJY202404006

地氯雷他定干混悬剂联合布地奈德对小儿慢性咳嗽的临床效果观察

Observation on the Clinical Effect of Desloratadine Dry Suspension Combined with Budesonide on Chronic Cough in Children

戴春宝1
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作者信息

  • 1. 350000 福建福州,福建省福州市长乐区妇幼保健院药剂科
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摘要

目的 探讨地氯雷他定干混悬剂与布地奈德联合应用对小儿慢性咳嗽的临床效果.方法 选取2022年1月至2023年6月期间在福州市长乐区妇幼保健院进行治疗护理的慢性咳嗽患儿100例,根据治疗方法不同随机分为两组,每组各50例,对照组采用布地奈德治疗,观察组患儿在对照组的基础上联合地氯雷他定干混悬剂,采用咳嗽症状积分、咳嗽特异性生活质量积分以及血清免疫球蛋白E水平对比两组患儿临床疗效.结果 干预前两组患儿日间咳嗽症状积分、夜间咳嗽症状积分、CQLQ评分及IgE水平比较无差异(P>0.05);干预后则均低于干预前,且观察组患儿均低于对照组(P<0.05).结论 对小儿慢性咳嗽应用地氯雷他定干混悬剂联合布地奈德治疗可降低患儿临床症状,提高患儿的生活质量.

Abstract

Objective To investigate the clinical effect of desloratadine dry suspension combined with budesonide on children with chronic cough.Methods 100 children with chronic cough who were treated and cared for in Changle District Maternal and Child Health Hospital of Fuzhou City from January 2022 to June 2023 were selected as the subjects of this study.According to different treatment methods,they were divided into two groups with 50 cases in each group,while the control group was treated with budesonide,and the observation group was treated with desloratadine dry suspension on the basis of the control group.Cough symptom score,cough specific quality of life score and serum immunoglobulin E level were used to compare the clinical efficacy of the two groups.Results Before intervention,there were no differences in daytime cough symptom score,nighttime cough symptom score,CQLQ score and IgE level between the two groups(P>0.05).After intervention,those of all children were lower than those fo them before intervention,and those of the observation group was lower than those of the control group(P<0.05).Conclusion Desloratadine dry suspension combined with budesonide can reduce the clinical symptoms and improve the quality of life of children with chronic cough.

关键词

地氯雷他定干混悬剂/布地奈德/咳嗽

Key words

Desloratadine dry suspension/Budesonide/cough

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出版年

2024
中华灾害救援医学

中华灾害救援医学

影响因子:0.796
ISSN:
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