中华灾害救援医学2024,Vol.11Issue(8) :885-888.DOI:10.13919/j.issn.2095-6274.ZHJY202407029

急性心肌梗死患者PCI术后住院期间心血管事件的相关因素分析

Analysis of Factors Related to Cardiovascular Events during Hospitalization after PCI in Patients with Acute Myocardial Infarction

修美玉
中华灾害救援医学2024,Vol.11Issue(8) :885-888.DOI:10.13919/j.issn.2095-6274.ZHJY202407029

急性心肌梗死患者PCI术后住院期间心血管事件的相关因素分析

Analysis of Factors Related to Cardiovascular Events during Hospitalization after PCI in Patients with Acute Myocardial Infarction

修美玉1
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作者信息

  • 1. 363200 福建漳州,漳浦县医院心血管内科
  • 折叠

摘要

目的 分析急性心肌梗死患者经皮冠脉介入(Percutaneous Coronary Intervention,PCI)术后住院期间心血管事件(Majoradverse Cardiac Events,MACE)的相关因素.方法 选取2022年2月到2024年2月在福建省漳浦县医院行PCI手术治疗的76例急性心肌梗死患者,根据术后是否出现MACE,分为MACE组(n=36例)和非MACE组(n=40例).统计术后MACE的发生情况,分别利用单因素方差分析和logistic回归分析,分析临床指标和实验室指标中的相关因素.结果 76例PCI治疗的急性心肌梗死患者中,36例患者发生MACE(47.37%),其中19例为急性心力衰竭(占52.78%)、15例为严重心律失常(占47.22%).研究发现,年龄≥ 65岁、高血脂、高血糖、心功能NYHA分级≥Ⅱ级、术后ST段回落不良、直接胆红素≥ 5.46 mmol/L、总胆固醇≥ 2.85 mmol/L、肌钙蛋白Ⅰ≥7.25μg/L、超敏C反应蛋白≥ 24.02 mg/L、N端前脑钠肽≥ 3874.57 mg/L是PCI术后MACE发生的危险因素;术前强化他汀治疗是MACE发生的保护因素.结论 PCI术后MACE发生率较高,且受多种因素影响,提前干预相关因素,可降低MACE的发生率.

Abstract

Objective To analyze the factors associated with major adverse cardiac events(MACE)during hospitalization after percutaneous coronary intervention(PCI)in patients with acute myocardial infarction.Meth-ods A total of 76 patients with acute myocardial infarction who underwent PCI at Zhangpu County Hospital,Fujian Province,from February 2022 to February 2024,were selected.Based on the occurrence of MACE postop-eratively,patients were divided into two groups:the MACE group(n=36)and the non-MACE group(n=40).The incidence of MACE was recorded,and both univariate analysis and logistic regression analysis were employed to examine the related factors among clinical and laboratory indicators.Results Among the 76 PCI-treated pa-tients,36(47.37%)experienced MACE,including 19 cases of acute heart failure(52.78%)and 15 cases of severe arrhythmia(47.22%).Risk factors for MACE after PCI included age ≥ 65,hyperlipidemia,hyperglycemia,NYHA heart function grade≥Ⅱ,poor ST-segment resolution postoperatively,hypertension,direct bilirubin ≥ 5.46 mmol/L,total cholesterol ≥ 2.85 mmol/L,troponin Ⅰ ≥ 7.25 μg/L,high-sensitivity C-reactive protein ≥ 24.02 mg/L,and N-terminal pro-B-type natriuretic peptide ≥ 3874.57 mg/L.Preoperative intensive statin therapy was identified as a protective factor against MACE.Conclusion The incidence of MACE after PCI is relatively high and influenced by multiple factors.Early intervention targeting these factors may reduce the occurrence of MACE.

关键词

心肌梗死/血管成形术,经腔,经皮冠状动脉/心血管疾病/心律失常,心性

Key words

myocardial infarction/angioplasty,balloon,coronary/cardiovascular diseases/arrhythmias,cardiac

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出版年

2024
中华灾害救援医学

中华灾害救援医学

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