中华灾害救援医学2024,Vol.11Issue(8) :909-911,918.DOI:10.13919/j.issn.2095-6274.ZHJY202407019

丙泊酚在无抽搐电休克治疗麻醉中的效果研究

Study on the Efficacy of Propofol in Anesthesia for Electroconvulsive Therapy without Convulsions

尧丽
中华灾害救援医学2024,Vol.11Issue(8) :909-911,918.DOI:10.13919/j.issn.2095-6274.ZHJY202407019

丙泊酚在无抽搐电休克治疗麻醉中的效果研究

Study on the Efficacy of Propofol in Anesthesia for Electroconvulsive Therapy without Convulsions

尧丽1
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作者信息

  • 1. 437300 湖北赤壁,赤壁市蒲纺医院麻醉科
  • 折叠

摘要

目的 探索研究无抽搐电休克治疗(Electroconvulsive Therapy,ECT)麻醉中应用丙泊酚的效果.方法 纳入2022年12月至2023年12月在赤壁市蒲纺医院接受无抽搐电休克治疗的200例患者为研究对象,根据使用药物的不同分为观察组与对照组,观察组采用丙泊酚进行麻醉,对照组采用硫喷妥钠进行麻醉,每组各100例.比较两组患者的麻醉情况、生命体征和不良反应发生情况.结果 观察组患者恢复自主呼吸所需时间和清醒所需时间均显著短于对照组(P<0.001).麻醉前,两组患者心率(Heart Rate,HR)、血氧饱和度(Oxygen Saturation,SpO2)、收缩压(Systolic Blood Pressure,SBP)均无显著差异(P>0.05);麻醉后,两组患者HR较麻醉前无显著改变(P>0.05),但SpO2、SBP较麻醉前降低(P<0.05);麻醉后两组患者HR、SpO2、SBP均无显著差异(P>0.05).观察组中有7例患者发生不良反应,不良反应发生率为7.00%,显著低于对照组的24例,对照组不良反应发生率为24.00%(P<0.001).结论 丙泊酚能够显著提升患者的麻醉效果,对患者HR、血压、SpO2的影响较小,不良反应发生率低,保障了麻醉的效果及安全性.

Abstract

Objective To investigate the effects of propofol in anesthesia for patients undergoing modified electroconvulsive therapy(ECT).Methods A total of 200 patients who received modified ECT at Pufang Hospi-tal in Chibi from December 2022 to December 2023 were included in the study.Based on the choice of anesthetic,patients were divided into two groups:the observation group(n=100,anesthetized with propofol)and the control group(n=100,anesthetized with thiopental sodium).The anesthetic effects,vital signs,and incidence of adverse re-actions were compared between the two groups.Results The time required to restore spontaneous breathing and to regain consciousness in the observation group was significantly shorter than in the control group(P<0.001).Be-fore anesthesia,there were no significant differences between the two groups in heart rate(HR),oxygen saturation(SpO2),and systolic blood pressure(SBP)levels(P>0.05).After anesthesia,HR did not significantly change from pre-anesthesia levels in either group(P>0.05),while SpO2 and SBP levels decreased compared to pre-anesthesia levels(P<0.05).Post-anesthesia,there were no significant differences between the two groups in HR,SpO2,and SBP levels(P>0.05).In the observation group,7 patients experienced adverse reactions(7.00%),significantly low-er than the 24 patients in the control group who experienced adverse reactions(24.00%),P<0.001.Conclusion Propofol effectively reduces the duration of anesthesia in patients undergoing modified ECT,has minimal impact on HR,blood pressure,and SpO2,and is associated with a low incidence of adverse reactions,thereby ensuring both the efficacy and safety of anesthesia.

关键词

电休克/麻醉/神经科学/心率

Key words

electroshock/anesthesia/neurosciences/heart rate

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出版年

2024
中华灾害救援医学

中华灾害救援医学

影响因子:0.796
ISSN:
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