摘要
目的 探索布地奈德治疗小儿急性喉炎的价值.方法 选取2021年2月至2024年2月于道真县人民医院就诊的小儿喉炎患者80例,根据治疗方案的不同分为布地奈德雾化吸入组(观察组)和地塞米松雾化吸入组(对照组),每组各40例.比较两组炎症因子水平、症状消失时间、临床有效率.结果 治疗前,两组患者CPR、PCT水平均无显著差异(P＞0.05);治疗后,两组患者以上炎症因子水平均降低(P＜0.05),且观察组炎症因子水平均低于对照组(P＜0.001).观察组临床症状咳嗽、发热、喉鸣、喉梗阻及呼吸困难消失的时间均比对照组短(P＜0.001).观察组临床有效率为95.00％(38/40),高于对照组的80.00％(32/40)(P＜0.05).结论 对于小儿急性喉炎采取布地奈德雾化吸入治疗可有效改善血清炎症因子的水平,缩短临床症状消失的时间,有效性较高.
Abstract
Objective Exploring the value of budesonide in the treatment of acute laryngitis in children.Methods Selecting 80 pediatric patients with laryngitis who received treatment at Daozhen County People's Hos-pital from February 2021 to February 2024,they weredivided into the budesonide nebulization inhalation group(observation group)and the dexamethasone nebulization inhalation group(control group)according to different treatment plans,with 40 cases in each group.We compared the levels of inflammatory factors,time to symptom res-olution,and clinical efficacy between two groups.Results Before treatment,there was no significant difference in CPR and PCT levels between the two groups of patients(P＞0.05);After treatment,the levels of inflammatory factors in both groups of patients decreased(P＜0.05),and the levels of inflammatory factors in the observation group were lower than those in the control group(P＜0.001).The observation group had a shorter time for the disap-pearance of clinical symptoms such as cough,fever,hoarseness,laryngeal obstruction,and dyspnea compared to the control group(P＜0.001).The clinical effective rate of the observation group was 95.00％(38/40),which was higher than the control group's clinical effective rate 80.00％(32/40)(P＜0.05).Conclusion Budesonide nebulization treatment for acute laryngitis in children can effectively improve serum inflammatory marker levels,shorten the du-ration of clinical symptoms,and demonstrate high efficacy.
基金项目
张家界市人民医院临床研究管理委员会课题(2022-LCYJ-020)
维普
万方数据