摘要
目的 对于重症肺炎患儿,鼻塞式持续气道正压通气的临床疗效和安全性进行探讨研究.方法 回顾性收集100例2021年1月至2024年1月石狮市妇幼保健院收治的重症肺炎患儿临床资料,根据所采取治疗方案的不同将其分为观察组(鼻塞式持续气道正压通气)和对照组(鼻导管吸氧),每组患儿均为50例.比较两组患儿临床疗效、临床相关症状缓解时间、血气相关指标、生命体征相关指标、PCIS评分以及安全性.结果 两组患儿治疗后临床总有效率观察组显著高于对照组(P<0.05).观察组患儿心率降至正常、呼吸困难缓解以及肺部啰音消失所需时间均较对照组患儿短(P<0.001).治疗前,两组患儿的PaO2、PaCO2、SaO2水平,呼吸频率和心率以及PCIS评分均无显著差异(P>0.05);治疗后,两组患儿以上指标水平均改善,且观察组患儿PaO2、SaO2水平、PCIS评分显著高于对照组(P<0.05);PaO2、PaCO2、呼吸频率和心率显著低于对照组(P<0.05),观察组患儿不良反应总发生率与对照组比较差异无统计学意义(P=0.002).结论 对于重症肺炎患儿,早期给予鼻塞式持续气道正压通气,可有效缩短临床症状缓解所需时间,纠正缺氧状态,提高临床疗效,安全性高.
Abstract
Objective Exploring the clinical efficacy and safety of nasal continuous positive airway pressure ventilation in children with severe pneumonia. Methods A retrospective collection of clinical data was conduct-ed on 100 children with severe pneumonia admitted to Shishi Maternal and Child Health Hospital from January 2021 to January 2024. According to the different treatment plans adopted,they were divided into an observation group (nasal continuous positive airway pressure ventilation) and a control group (nasal cannula oxygen inhalation),with 50 children in each group. Compare the clinical efficacy,clinically relevant symptom relief time,blood gas re-lated indicators,vital sign related indicators,PCIS score,and safety between two groups of pediatric patients. Re-sults The total clinical effective rate of the observation group after treatment was significantly higher than that of the control group (P<0.05). The observation group had a shorter time for heart rate to return to normal,breathing difficulties to alleviate,and lung rales to disappear compared to the control group (P<0.001). Before treatment,there were no significant differences in the levels of PaO2,PaCO2,SaO2,respiratory rate,heart rate,and PCIS score between the two groups of children (P>0.05);After treatment,the levels of the above indicators in both groups of children improved,and the PaO2,SaO2 levels,and PCIS scores in the observation group were significantly higher than those in the control group (P<0.05);PaO2,PaCO2,respiratory rate,and heart rate were significantly lower in the observation group than in the control group (P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the observation group and the control group (P=0.002). Conclusion Early nasal continuous positive airway pressure ventilation in children with severe pneumonia can effectively shorten the time required for clinical symptom relief,correct hypoxia,improve clinical efficacy,and have high safety.
维普
万方数据