Objective To study the influencing factors of infection after holmium laser lithotripsy and the clinical effect of the application of Antimicrobial Stewardship(AMS)mode.Methods 180 patients with ureteral calculi who underwent holmium laser lithotripsy in our hospital from January 2021 to December 2021 were retrospective analyzed.The incidence of postoperative infection was 14.44%(26/180)as the infection group and the rest 154 cases were selected as the uninfected group.The clinical data of the patients were collected and the influencing factors of postoperative infection were analyzed.Among the 180 patients,107 were treated with antibiotics during the perioperative period,and the incidence of postoperative infection was 10.28%.The patients selected during this period received the traditional antibiotic drug management method,so they were set as the pre-intervention group(n=107).The patients who underwent holmium laser lithotripsy for ureteral calculi from January 2022 to December 2022 were selected in equal proportion,and the patients received the AMS model during this period(set as the post-intervention group).The application of an-tibiotics and the incidence of postoperative infection were compared between the two groups.Results Univariate analysis showed that diabetes,op-eration time,double J tube indwelling time,long hospital stay,large stone diameter,no use of antibiotics during perioperative period,large stone load,and hydronephrosis were related to postoperative infection.After analysis,the proportion of preoperative＜2 h medication,postoperative withdrawal time＜24 h,24-48 h,unreasonable drug selection,unreasonable combination medication,and postoperative infection rate in the post-intervention group were lower than those in the pre-intervention group(P＜0.05).Conclusion The infection after holmium laser lithotripsy for ureteral calculi is related to many factors.The AMS model is helpful to establish the standard of antibiotic management and improve the rational use of antibiotics in hospitals,so as to reduce the postoperative infection rate.
维普
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