首页|子宫内膜息肉患者宫腔镜术后自然妊娠的影响因素探讨

子宫内膜息肉患者宫腔镜术后自然妊娠的影响因素探讨

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目的 通过对子宫内膜息肉患者行宫腔镜微创电切术,观察其影响术后临床结局的独立危险因素.方法 选择 98例子宫内膜息肉患者作为研究对象,患者均实施宫腔镜电切手术.根据 1年内子宫内膜息肉患者妊娠情况,将其分为未妊娠组、妊娠组,采用单因素分析一般临床资料,利用Logistic回归模型评估子宫内膜息肉宫腔镜术后临床结局的多因素分析,利用ROC曲线评估相关指标对子宫内膜息肉宫腔镜术后预后情况的效能分析.结果 术后 1 年妊娠患者为 67例,未妊娠患者为 31例.单因素结果显示:年龄、息肉直径、息肉数量、雌激素受体、孕激素受体表达水平是影响子宫内膜息肉宫腔镜术后临床结局的相关因素(P<0.05);多因素分析结果显示:年龄≥35岁、息肉直径≥10 mm、息肉个数多、雌激素受体及孕激素受体不均衡表达是子宫内膜息肉宫腔镜术后临床结局的独立危险因素(P<0.05);以临床病理结果为标准,年龄≥35 岁、息肉直径≥10 mm、息肉个数多及其联合预测对患者预后情况均具有一定效能,其中联合预测的效能最高(AUC=0.858).结论 年龄≥35岁、息肉直径≥10 mm、息肉个数多、雌激素受体及孕激素受体不均衡表达是子宫内膜息肉宫腔镜术后临床结局的独立危险因素.
The influence factors of spontaneous pregnancy in patients with endometrial polyp after hysteroscopic operation
Objective To observe the independent risk factors affecting the postoperative clinical outcome of patients with endometrial polyps by hysteroscopic minimally invasive electroresection.Methods 98 patients with endometrial polyps who underwent hysteroscopic resection were se-lected as the study objects.According to the pregnancy status within 1 year,they were divided into non-pregnant group and pregnant group.The gen-eral clinical data were analyzed by single factor,the multivariate analysis of clinical outcome after hysteroscopic operation of endometrial polyps was evaluated by Logistic regression model,and the efficacy analysis of relevant indicators on prognosis after hysteroscopic operation of endometrial polyps was evaluated by ROC curve.Results There were 67 pregnant patients and 31 non-pregnant patients 1 year after operation.Single factor results showed that age,polyp diameter,number of polyps,estrogen receptor and progesterone receptor expression levels were related to the clinical outcome of endometrial polyps after hysteroscopic surgery(P<0.05).Multivariate analysis showed that age≥35 years old,polyp diameter≥10 mm,large num-ber of polyps,unbalanced expression of estrogen receptor and progesterone receptor were independent risk factors for clinical outcomes of endometrial polyps after hysteroscopic surgery(P<0.05).According to the clinicopathological results,age≥35 years,polyp diameter≥10 mm,polyp number and combined prediction had certain efficacy on the prognosis of patients,and the combined prediction had the highest efficacy(AUC =0.858).Conclusion Age≥35 years,polyp diameter≥10 mm,large number of polyps,unbalanced expression of estrogen receptor and progesterone receptor are independent risk factors for clinical outcomes of endometrial polyps after hysteroscopic surgery.

Endometrial polypHysteroscopic electrotomyEstrogen receptorPostoperative pregnancyInfluencing factor

王泉梅、赵倩

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311500 桐庐,浙江省桐庐县第一人民医院

子宫内膜息肉 宫腔镜电切术 雌激素受体 术后妊娠 影响因素

杭州市卫生科技计划项目

B20230155

2024

浙江创伤外科
温州医学院

浙江创伤外科

影响因子:0.884
ISSN:1009-7147
年,卷(期):2024.29(1)
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