The efficacy and safety of pterygium resection combined with autologous corneal limbal stem cell transplantation for the treatment of pri-mary pterygium
Objective To explore the clinical efficacy and safety of pterygium resection combined with autologous corneal limbal stem cell transplantation for the treatment of primary pterygium.Methods A retrospective study was conducted on the medical records of 66 patients who underwent primary pterygium surgery in our hospital from January 2019 to January 2023.66 patients were divided into the control group(n=33,ptery-gium resection combined with free conjunctival flap transplantation)and the experimental group(n=33,pterygium resection combined with autologous corneal limbal stem cell transplantation),based on different surgical methods.The clinical outcomes,postoperative conjunctival flap healing time,and corneal epithelial repair time were compared.The changes in tear film rupture time(TBUT)before and 1 month,3 months,and 6 months after surgery,as well as the incidence of postoperative complications and recurrence rate at 6 months after surgery were recorded.Results The clinical efficacy of the experimental group patients after treatment was higher than that of the control group,with significantly shorter postoperative conjunctival flap healing time and corneal epithelial repair time compared to the control group,the TBUT time was significantly longer than that of the control group at 1 month,3 months,and 6 months after surgery(P＜0.05).There was no significant difference in the incidence and recurrence rates of postoperative complications between the two groups(P＞0.05).Conclusion The combination of pterygium resection and autologous corneal limbal stem cell trans-plantation has good therapeutic effects and safety in the treatment of primary pterygium,which can reduce the postoperative recurrence rate without increasing the incidence of postoperative complications.
Primary pterygiumExcision of pterygiumAutologous corneal limbal stem cell transplantationEffect
NETL
NSTL
万方数据
维普
