Analysis of related influencing factors on radiation induced oral mucositis in patients with head and neck tumor radiotherapy
Objective To study on the related influencing factors of radiation-induced oral mucosal inflammation in patients with head and neck tumor radiotherapy.Methods A retrospective analysis was conducted on the clinical data of 130 patients with head and neck tumor radio-therapy admitted to our hospital from October 2020 to October 2023.The patients were divided into the study group(occurrence,n=110)and the con-trol group(no occurrence,n=20)based on the incidence of radiation-induced oral mucositis.Single factor χ2 inspection and multivariate logistic re-gression analysis were applied to analyze the relevant influencing factors of radiation induced oral mucosal inflammation in patients.Results The results of univariate analysis showed that the incidence of radiation induced oral mucositis was related to history of smoking,induction chemotherapy,oral hygiene status,and use of oral mucosal protectants(P<0.05).The results of multivariate logistic regression analysis showed that the occurrence of radiation-induced oral mucositis was related to induced chemotherapy,no use of mucosal protectants,smoking,and poor oral hygiene,it was an inde-pendent risk factor for radiation-induced oral mucositis(P<0.05).Conclusion Patients with head and neck tumors undergoing radiotherapy have a higher risk of developing radiation-induced oral mucosal inflammation.The radioactive oral mucositis is associated with induced chemotherapy,no use of mucosal protective agents,smoking,and poor oral hygiene,which are independent risk factors,therefore,targeted prevention can be made in clini-cal work to reduce the risk of radioactive oral mucositis.
Head and neck tumorsRadiation induced oral mucosal inflammationRadiation therapyMalignant tumorsInfluence factor
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