首页|整形保乳手术治疗早期三阴乳腺癌的效果评价

整形保乳手术治疗早期三阴乳腺癌的效果评价

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目的 分析整形保乳手术治疗早期三阴乳腺癌的效果.方法 回顾性分析2019年1月至2022年1月本院收治的89例早期三阴乳腺癌患者的临床资料,将其分为采用常规保乳手术治疗的对照组(45例)和采用整形保乳手术治疗的研究组(44例),分组方法为手术方法不同.两组均术后随访2年.比较两组手术相关参数,血清YKL-40、TGF-β、CA153水平(术前及术后6个月),并发症发生情况(住院期间),以及生存、复发、转移情况及乳房美观度(术后2年).结果 研究组切除标本体积较大,手术时间及切除标本手术切缘(最小、最大)较长,住院时间较短(组间比较),差异有统计学意义(P<0.05);对照组、研究组比较,两组血清YKL-40、TGF-β、CA153水平均降低(术后6个月相较于术前),有差异(P<0.05);术后2年,对照组、研究组比较,后者乳房美观总优良率高于前者,差异有统计学意义(P<0.05).结论 相较于常规保乳手术,早期三阴乳腺癌患者应用整形保乳手术不仅能够保障肿瘤控制效果,还可提升乳房美观度.
Effect evaluation of plastic breast conserving surgery in the treatment of early triple negative breast cancer
Objective To analyze the effect of plastic breast-conserving surgery in the treatment of early triple negative breast cancer.Methods The clinical data of 89 patients with early triple negative breast cancer admitted to our hospital from January 2019 to January 2022 were analyzed retrospectively.They were divided into the control group(45 cases)treated with conventional breast-conserving surgery and the research group(44 cases)treated with plastic breast-conserving surgery.Both groups were followed up for 2 year after operation.The operation-related parame-ters,the levels of serum YKL-40,TGF-β,CA153,(before and 6 months after operation),incidence of complications(during hospitalization),survival,recurrence,metastasis and breast beauty(2 years after operation)were compared between the two groups.Results The volume of excised specimens of the research group was larger,the operation time and surgical margin of excision specimen(minimum and maximum)of the research group were longer,and the hospitalization time of the research group was shorter than those of the control group(P<0.05).Compared with the control group and the research group,the levels of serum YKL-40,TGF-β,CA153 of the two groups decreased(6 months after operation compared with before opera-tion)(P<0.05).2 years after operation,compared with the control group and the research group,the overall excellent and good rate of the latter was higher than that of the former(P<0.05).Conclusion Compared with conventional breast-conserving surgery,the application of plastic breast-con-serving surgery in patients with early triple-negative breast cancer can not only ensure the tumor control effect,but also improve the beauty of breast.

Triple negative breast cancerPlastic breast-conserving surgeryTumor markersBeauty of breast

张婷婷

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310053 杭州,浙江中医药大学

浙江省杭州市肿瘤医院

三阴乳腺癌 整形保乳手术 肿瘤标志物 乳房美观度

2024

浙江创伤外科
温州医学院

浙江创伤外科

影响因子:0.884
ISSN:1009-7147
年,卷(期):2024.29(8)